Navigation Links
Micromet is Presenting Four Posters on BiTE(R) Antibodies at the International AACR-NCI-EORTC Conference
Date:10/23/2007

Presentation on MCSP-specific BiTE Antibody Selected by AACR for Press

Coverage

BETHESDA, Md., Oct. 23 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company focusing on the development of novel, proprietary antibody-based products for cancer, inflammation and autoimmune diseases, today announced that data on two antibodies developed using BiTE(R) technology will be reported at the joint international meeting of the American Association for Cancer Research (AACR), National Cancer Institute (NCI) and European Organization for Research and Treatment of Cancer (EORTC) being held in San Francisco, CA, from October 22-26. The new findings relate to the mode of action, target biology and therapeutic window for two new BiTE antibodies in pre-clinical development.

BiTE antibodies are T cell recruiting antibodies designed to transiently connect cytotoxic T cells with malignant cancer cells, which has been shown to result in the eradication of cancer cells. The four posters report on the EpCAM (CD326)-specific BiTE antibody MT110, and on a novel BiTE antibody which targets melanoma-associated chondroitin sulfate proteoglycan (MCSP). MT110 is being developed for the treatment of a variety of adeno and squamous cell carcinoma which overexpress EpCAM, while the BiTE antibody which binds to MCSP is being developed for the treatment of metastatic melanoma and other cancers expressing MCSP.

The first poster presentation shows that BiTE antibodies which target the cancer associated antigen MCSP are highly active against melanoma cells by recruiting T cells for efficient tumor cell lysis in vitro (abstract A61). This poster has been selected for inclusi
'/>"/>

SOURCE Micromet, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
2. Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
3. Quality control of antibodies using the 2100 bioanalyzer and the Protein 200 Plus assay
4. Mirus announces new method for making antibodies
5. Olympics of biotechnology has international flavor
6. Traffic data firm navigates international business
7. Catalyst International profit exceeds expectations
8. Lack of broadband hamstrings international videoconferencing
9. 30 days to success: Three simple steps to create your own international startup
10. TEKLYNX International announces new RFID software
11. Ruling enforces international trademark electronic filing requirements

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...re/--Formanybusinesses,2009hasbeenapainfulyear.Not...ngnetworkofexpertphysiciansspecializingexclusively...wnthenumberof physiciansinitsnetwork sinceNove...dmorephysician-ownedcenters,includingoneinPuertoRi...gicMDhasopened13newbioidenticalhormonespecialtypra...
(Date:11/25/2009)...r.comannouncesthatanewmarketresearchreportisavaila...alysisandForecaststo2013 ,, http://www.report...sis-and-Forecasts-to-2013.html ,, BrazilBioeth...y ,, Thereportprovidesdetailedanalysisandforec...nolmarketinparticular.Italsohelpsinanalyzingandfor...
(Date:11/24/2009)...ES(Nasdaq: IESC ),aleadingnationalproviderofelectr...rcial,industrialandresidentialmarkets,announcedtod...tractfromManhattanTorconJVtoinstalltheelectricalsy...cilityattheU.S.ArmyMedicalResearchInstituteofInfec.... ,, ThenewUSAMRIIDreplacementfacilitywilladdap...
(Date:11/24/2009)...omoreprestigiousuniversitieshavejoinedBioCareerCen...forlifescienceprofessionals. ,, Northwesternand...ng28othermajorlifesciencetrainingInstitutions. ,...post-graduatesinthelifesciences.Whiletherearehundr...Centeristheonlyonethatserveslifesciencepost-gradua...
Breaking Biology Technology:Nation's Largest Network of Doctors Specializing in Bioidentical Hormones Grows at an Exponential Rate 2Nation's Largest Network of Doctors Specializing in Bioidentical Hormones Grows at an Exponential Rate 3Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 3Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 4Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 5Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 6Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 7Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 8Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 9Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2Two Major Universities Join Nation's Leading Postgrad Bio Job Board 2
...KVILLE, Md., Aug. 31 Human Genome,Sciences, Inc. ...tion at the,Thomas Weisel Partners Annual Healthca...at http://www.hgsi.com . (Logo: http://www.news... of Human Genome Sciences, senior management team ...ay, September 5, 2007 at 1:30 pm,Eastern Time. In...
...day, August 31, 9:15 am ET, LOS ANGELES, Aug. 31 ...President and acting Chief Executive, has release,...tion into the Presidency,last month: 1. Dr. Harmi... several positions that were producing no reve...ults for the Company, in his view. That was done ...
...C-Accredited Workshop Set for Sept. 3, UPPSALA, S...M.D., Ph.D., and Bernard de Bruyne, M.D., Ph.D., w...ssure, or Fractional Flow Reserve (FFR),in improvi...t the European,Society of Cardiology (ESC) Congres...ich is sponsored by Radi Medical Systems, will tak...
Other Biology Technology:Signalife Provides Corporate Update 2Signalife Provides Corporate Update 3Interventional Cardiologists Nico Pijls, Bernard De Bruyne to Discuss Benefits of Measuring Coronary Pressure in Improving Multivessel PCI at ESC Congress 2007 2
(Date:11/24/2009)...ystallised a protein that may help gut bacteria bi...d be used by probiotic producers to identify strai.... , "Probiotics need to interact with cells linin... attach to surfaces in the gut they are more likel...ity," says Dr Nathalie Juge from the Institute of ...
(Date:11/24/2009)...W YORK (November 24, 2009) -- The Wildlife Conserv...ling that the last remaining population of Siberia...the rising tide of poaching and habitat loss. , ...ussian officials of what needs to be done to prote...t. , The report was released by the...
(Date:11/24/2009)...vailable in Spanish . , The presence of inc...flammatory substances in the blood, hinders the lo...esearch project of the University of Navarra condu...he School of Pharmacy. , The project, entitled "...to the control of body weight and inflammation," e...
Breaking Biology News(10 mins):A sticky solution for identifying effective probiotics 2Report shows dramatic decline in Siberian tigers 2It can be predicted the reaction obese patients will have to a diet 2Enzyme doesnt act alone in atrial fibrillation 8877 1Enzyme doesnt act alone in atrial fibrillation 8877 2The bitter side of sweeteners 8874 1The bitter side of sweeteners 8874 2BenefitMall Hosts New World of Healthcare Forum to Empower Partners to Find Solutions for Volatile Healthcare Industry 49218 1BenefitMall Hosts New World of Healthcare Forum to Empower Partners to Find Solutions for Volatile Healthcare Industry 49218 2BenefitMall Hosts New World of Healthcare Forum to Empower Partners to Find Solutions for Volatile Healthcare Industry 49218 3
... by Princeton University scientists has found for ...part of the Earth,s ecosystem, rely on the rare tr...tilizer needed to support their wildly productive ...pid, lush growth of rainforests comes from tiny ba...ilizer in the soil. , Until now, scientists had t...
...learners? Can we teach everybody to be like them? ...ct recently funded by the National Science Foundat...o game technology to codify learning systems in wa... from sports to surgery. , Two Rice professors, M... on O,Malley,s pioneering work using robots to tre...
...owerful new analysis methods and abundant data fro...rd into a new era. Bacteria in particular are shed... processes of interest not just within microbiolog...embracing higher organisms, including plants and v...improved knowledge of how bacteria behave when ins...
Other Biology News:Princeton-led team finds secret ingredient for the health of tropical rainforests 2Wii bit of fun at Rice University has serious intent 2Computation and genomics data drive bacterial research into new golden age 2Computation and genomics data drive bacterial research into new golden age 3
... in one-step QRT-PCR reactions, with gene-specific...fer a quick and simple method for analysing RNA. T...col easy to follow and automation possible. ,The 2... blend of RTases combining the advantages of AMV a...
SphingoBeads from Echelon Biosciences Inc.
...E P Q H P P G P P T M D L E(19) PA1-072 detects mu...ls.,PA1-072 has been successfully used in Wes...ody detects an ~86 kDa protein representing Mint3 ...eptide corresponds to amino acid residues 1-19 fro...
Rabbit Anti-Staphylococcus Enterotoxin A Polyclonal Antibody, Horseradish Peroxidase Conjugated from Abcam
Biology Products: