Navigation Links
Micromet is Presenting Four Posters on BiTE(R) Antibodies at the International AACR-NCI-EORTC Conference
Date:10/23/2007

Presentation on MCSP-specific BiTE Antibody Selected by AACR for Press

Coverage

BETHESDA, Md., Oct. 23 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company focusing on the development of novel, proprietary antibody-based products for cancer, inflammation and autoimmune diseases, today announced that data on two antibodies developed using BiTE(R) technology will be reported at the joint international meeting of the American Association for Cancer Research (AACR), National Cancer Institute (NCI) and European Organization for Research and Treatment of Cancer (EORTC) being held in San Francisco, CA, from October 22-26. The new findings relate to the mode of action, target biology and therapeutic window for two new BiTE antibodies in pre-clinical development.

BiTE antibodies are T cell recruiting antibodies designed to transiently connect cytotoxic T cells with malignant cancer cells, which has been shown to result in the eradication of cancer cells. The four posters report on the EpCAM (CD326)-specific BiTE antibody MT110, and on a novel BiTE antibody which targets melanoma-associated chondroitin sulfate proteoglycan (MCSP). MT110 is being developed for the treatment of a variety of adeno and squamous cell carcinoma which overexpress EpCAM, while the BiTE antibody which binds to MCSP is being developed for the treatment of metastatic melanoma and other cancers expressing MCSP.

The first poster presentation shows that BiTE antibodies which target the cancer associated antigen MCSP are highly active against melanoma cells by recruiting T cells for efficient tumor cell lysis in vitro (abstract A61). This poster has been selected for inclusi
'/>"/>

SOURCE Micromet, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling
2. Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
3. Quality control of antibodies using the 2100 bioanalyzer and the Protein 200 Plus assay
4. Mirus announces new method for making antibodies
5. Olympics of biotechnology has international flavor
6. Traffic data firm navigates international business
7. Catalyst International profit exceeds expectations
8. Lack of broadband hamstrings international videoconferencing
9. 30 days to success: Three simple steps to create your own international startup
10. TEKLYNX International announces new RFID software
11. Ruling enforces international trademark electronic filing requirements

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2009)...RORA, Ontario, Nov. 6 He...: HXBPF) today announced that John Docherty, presi...Merriman Curhan Ford,s 6th annual Investor Summit ...el in New York City. Mr. Docherty will provide an...ment programs L-DOS47 and Topical Interferon Alpha...
(Date:11/6/2009)...RING VALLEY, Calif., Nov. 6 Calbio...d a Small Business Innovative Research (SBIR) Phas... Material command. Under terms of the agreement, C...ASRs) for the diagnosis of Dengue virus. ,, ...presents a major threat to military forces deploye...
(Date:11/5/2009)...NSPORTATION -- Gone hybrid . . . , Fuel econom...are now posted at the www.fueleconomy.gov web si...and maintains for the U.S. Department of Energy an...f the top 10 vehicles on the best fuel economy lis...1 MPG city; 48 highway). "This list proves that hy...
(Date:11/5/2009)...N DIEGO, Nov. 5 Imagenet...ay that William Spencer, President and CEO of Imag...the 2nd annual LD MICRO Conference on Thursday, De...Los Angeles. ,, About LD MICRO ,, LD MICRO i...s on finding undervalued companies in the micro-ca...
Breaking Biology Technology:Helix BioPharma to Present at Merriman Curhan Ford's Investor Summit 2009 on November 10th 2Helix BioPharma to Present at Merriman Curhan Ford's Investor Summit 2009 on November 10th 3Calbiotech Awarded U.S. Army Phase I SBIR Research Contract to Develop Analyte Specific Reagents for the Diagnosis of Dengue Fever Virus 2November 2009 story tips from the US Department of Energy's Oak Ridge National Laboratory 2November 2009 story tips from the US Department of Energy's Oak Ridge National Laboratory 3Imagenetix to Present at 2nd Annual LD MICRO Conference at the Luxe Sunset Bel Air 2
...GA, ON, Oct. 11 /PRNewswire-FirstCall/ - YM BioSci...logy company that identifies, develops,and commerc...wide, today,advised that its Annual Meeting of Sha...t 4:00pm at the Gallery of the TSX Broadcast & Con...t West, Toronto, Ontario. The items for considera...
... Oppose Proposal to Kill Human Embryos for Researc...ference President and Chief Executive Officer Sist...atement today regarding the formation of the,ballo...In order to protect human life at its most vulnera...ated, that seeks to clone and/or kill,human embryo...
...zerland, October 11 The young Swiss biotech,enter... Michel Klein, one,of the world,s most renowned va...ice President of Science & Technology of the Avent...ship of the scientific sector of,vaccine developme...as,access to an outstanding network across one of ...
Other Biology Technology:YM BIOSCIENCES NOTICE OF ANNUAL MEETING OF SHAREHOLDERS AND NOMINATION OF DIRECTORS 2YM BIOSCIENCES NOTICE OF ANNUAL MEETING OF SHAREHOLDERS AND NOMINATION OF DIRECTORS 3Prof. Michel Klein Becomes Chief Scientific Officer at AMVAC 2
(Date:11/9/2009)... a wet ethanol production method that begins by so...lts in more gallons of ethanol and more usable co-...or their buck by about 20 percent. , "The conve... but other than distillers dried grains with solub...niversity of Illinois Agricultural Engineer Esha K...
(Date:11/9/2009)... Ala. The U.S. Department of Energy (DOE) has ann... Alabama at Birmingham (UAB) School of Engineering... gas emissions through the capture and permanent s...CO2). The project is in collaboration with Souther... Funded by the DOE through the 2009 American Reco...
(Date:11/9/2009)...nce of butterfly wings has inspired a 3.2m, three-...ovation in the fields of security, energy and the ...ional technology company QinetiQ have just signed ...es based on groundbreaking physical sciences resea...icists from the University of Exeter and QinetiQ w...
Breaking Biology News(10 mins):Wet ethanol production process yields more ethanol and more co-products 2UAB, partners seek safe carbon dioxide storage for 'greener' power generation 2UAB, partners seek safe carbon dioxide storage for 'greener' power generation 3£3.2m ($5.4 million) research project to capture brilliance of butterfly wings 2Cyberonics to Present at UBS Global Life Sciences Conference 56756 1Cyberonics to Present at UBS Global Life Sciences Conference 56756 2Access Pharmaceuticals Provides Update on ProLindac 28TM 29Clinical Development Plan 13977 1Access Pharmaceuticals Provides Update on ProLindac 28TM 29Clinical Development Plan 13977 2Access Pharmaceuticals Provides Update on ProLindac 28TM 29Clinical Development Plan 13977 3Access Pharmaceuticals Provides Update on ProLindac 28TM 29Clinical Development Plan 13977 4Research Demonstrates that HerbalSciences Proprietary Elderberry Extract Prevents in Vitro H1N1 Influenza Infection 56753 1Research Demonstrates that HerbalSciences Proprietary Elderberry Extract Prevents in Vitro H1N1 Influenza Infection 56753 2Research Demonstrates that HerbalSciences Proprietary Elderberry Extract Prevents in Vitro H1N1 Influenza Infection 56753 3
...ions will converge in Taipei amid spiralling inter... others beginning to realize potential application...and food safety to disease prevention and better e...geoning three-year-old scientific field could, amo...mber out of global markets, slow the spread of inv...
...ield of HIV research through his rational approach...n HIV vaccine. His method is based on gaining an ...ul antibodies generated to date, and the sites on ...hat will be essential to designing improvements to... published an extensive number of papers, four of ...
... 2007 American Society for Microbiology (ASM) ICAA... Company, Inc., U.S. Human Health, will be present...ant Professor in Pediatrics, Division of Pulmonary...al Center, Seattle, Washington. Dr. Hoffman is be...ology and infectious disease. , Dr. Hoffman has...
Other Biology News:Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 2Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 3Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 4Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 5Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 6Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 7Amid spiralling government interest, world's top 350 DNA barcode scientists meet in Taipei 8
...gands\n\nReceptor-related research has long been e...abeled ligands selected to keep pace with new disc...ts and services for receptor research and drug dis...igands. If you do not find exactly what you need, ...
...ve and specific detection of microRNAs (miRNAs) by...ave high binding affinity and discrimination, enab...s. Due to the high binding affinity of the miRCURY... needed compared to traditional probes. Furthermor...
Rabbit Anti-Mouse Vitronectin Polyclonal Antibody, Unconjugated from Abcam
...methylation is an irreversible post translational ...o protein activity. At least three types of PRMT e...ese enzymes have been shown to have essential regu... several fundamental areas. These protein include ...
Biology Products: