rials, while the remainder of the product pipeline is in preclinical
development. The BiTE(R) antibody MT103 is in a phase 2 clinical trial for
the treatment of patients with acute lymphoblastic leukemia and in a phase
1 clinical trial for the treatment of patients with non-Hodgkin's lymphoma.
BiTE antibodies represent a new class of antibodies that activate a
patient's own cytotoxic T cells, considered the most powerful "killer
cells" of the human immune system, to eliminate cancer cells. Micromet is
developing MT103 in collaboration with MedImmune, Inc., a subsidiary of
AstraZeneca plc. The second clinical stage antibody is adecatumumab, also
known as MT201, a human monoclonal antibody which targets epithelial cell
adhesion molecule (EpCAM)-expressing solid tumors. Micromet is developing
adecatumumab in collaboration with Merck Serono in a phase 1b clinical
trial evaluating adecatumumab in combination with docetaxel for the
treatment of patients with metastatic breast cancer. The third clinical
stage antibody, MT293 is licensed to TRACON Pharmaceuticals, Inc. and is
being developed in a phase 1 clinical trial for the treatment of patients
with cancer. In addition, Micromet has established a collaboration with
Nycomed for the development and commercialization of MT203, a human
antibody neutralizing the activity of granulocyte/macrophage colony
stimulating factor (GM-CSF), which has potential applications in the
treatment of various inflammatory and autoimmune diseases, such as
rheumatoid arthritis, psoriasis, or multiple sclerosis.
Forward-Looking Statements
This release contains certain forward-looking statements that involve
risks and uncertainties that could cause actual results to be materially
different from historical results or from any future results expressed or
implied by such forward-looking statements. Such forward-looking statements
include statements regarding the efficacy, safety, and intended utilization
of Micromet's product candidate
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SOURCE Micromet, Inc. Copyright©2008 PR Newswire. All rights reserved | |
Page: 1 2 3 4 5 6 7 8 9 Related biology technology :1.
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