Navigation Links
Microbia and Forest Laboratories Announce Linaclotide Co-Development and Co-Marketing Collaboration
Date:9/17/2007

ment options. Chronic constipation and IBS-C patients are treated largely by primary care physicians, where the Forest sales force has already built excellent relationships. We are particularly excited to be working closely with Microbia, an innovative pharmaceutical company with a strong and proven management and scientific team."

Linaclotide is currently undergoing Phase 2b clinical testing in patients with IBS-C and CC. In earlier clinical studies, linaclotide demonstrated improved bowel function in patients with IBS-C and CC. These studies also showed linaclotide was well tolerated with a low incidence of adverse events. Linaclotide is an agonist of the guanylate cyclase type-C receptor found in the intestine and acts by a mechanism distinct from previously developed products for IBS-C and CC. Linaclotide is administered orally but acts locally in the intestine with no measurable systemic exposure. Microbia and Forest intend to initiate Phase 3 studies in the second half of 2008.

"Joining forces with Forest is the best way to maximize linaclotide's value for patients and investors," said Peter Hecht, Microbia's Chief Executive Officer. "Forest uniquely combines world-class primary care commercial capabilities and an entrepreneurial and collaborative culture. Our companies share a common vision and commitment for getting linaclotide to IBS-C and CC sufferers."

About Irritable Bowel Syndrome (IBS)

One out of six adults in developed countries suffers from IBS, a chronic condition marked by abdominal pain and disturbed bowel function. IBS accounts for 12% of adult visits to primary care physicians and is the most common disorder diagnosed by gastroenterologists. Health care costs associated with IBS exceed $25 billion annually. IBS patients fall into three subgroups- constipation-predominant (IBS-C), diarrhea-predominant (IBS-D), and alternating (IBS-A)-and 30% to 40% of these patients suffer from IBS-C. There are currently few available ther
'/>"/>

SOURCE Forest Laboratories, Inc.; Microbia, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Microbial Diversity in Ground and Surface Water Analyzed by Denaturing Gradient Gel Electrophoresis Using the DCode System
2. Monitoring Microbial Populations Using Real-Time qPCR on the MJ Research Opticon 2 System
3. Scaling-Up from Spinners, T-Flasks & Shakers: A versatile bioreactor for mammalian and microbial cells
4. DeForest biodiesel plant begins production
5. Biodiesel plant being built in DeForest to make alternative fuel
6. Use of X-rays to advance wood-decay knowledge leads to honor for Forest Products Lab biologist
7. Biodiversity threatened as forests become islands of green, UW professor says
8. BioRobot MDx standardize your automated protocols in clinical laboratories
9. Distance-Learning Remote Laboratories using LabVIEW
10. States are the best laboratories for healthcare reform
11. Scientific Protein Laboratories Acquired by New York firm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... PharmaBoardroom,s new report, , Healthcare and ... free download , digs deep into this vibrant market, ... sector today. One area where Algeria ... a homegrown pharmaceutical manufacturing base, even if the government,s ambitious ... off. A cursory comparison with neighboring Morocco ...
(Date:12/22/2014)... 22, 2014 The Center for ... of technical training across the life sciences industry, has ... (SCDM) to provide the organization's members with discounted ... access to the more than 350 sessions across 80 ... 10% off when registering for a public course ...
(Date:12/22/2014)... DIEGO , Dec. 22, 2014 GenomeDx ... the Decipher Prostate Cancer Classifier, a genomic test for ... in node-negative, high-risk men managed by radical prostatectomy without ... radical prostatectomy is relatively uncommon, using tumor genomics to ... of metastatic disease is an important advance. The study ...
(Date:12/22/2014)... Fertility Associates of Memphis has announced a ... a network of more than 20 contributing fertility ... fast access to a national pool of frozen ... Associates of Memphis is the only fertility clinic in ... Dr. William Kutteh , director of Fertility Associates ...
Breaking Biology Technology:PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
... Alfacell Corporation,(Nasdaq: ACEL ) today announced that ... 29, 2008 notifying the Company that its,securities will ... June 25,2008, NASDAQ notified the Company that the ... the minimum $35 million required for continued,inclusion on ...
... FALLS, N.J., Aug. 1 CANTEL MEDICAL,CORP. (NYSE: ... Crosstex,International, Inc. subsidiary, effective today. As planned, Richard ... retired effective today,after over 50 years with Crosstex, ... Gary Steinberg and Mitchell Steinberg, also,former owners of ...
... and ... Diagnostic System, ... announced it has entered into a non-binding letter of,intent to ... real-time wireless beat-to-beat, intelligent heart monitor and,diagnostic system, designed for ...
Cached Biology Technology:Alfacell Receives NASDAQ Delisting Letter 2Alfacell Receives NASDAQ Delisting Letter 3Cantel Medical Announces Management Succession at Crosstex Healthcare Disposables Subsidiary 2Bioheart, Inc., Announces Letter of Intent to Acquire MEDICALGORITHMICS, Ltd. 2Bioheart, Inc., Announces Letter of Intent to Acquire MEDICALGORITHMICS, Ltd. 3Bioheart, Inc., Announces Letter of Intent to Acquire MEDICALGORITHMICS, Ltd. 4Bioheart, Inc., Announces Letter of Intent to Acquire MEDICALGORITHMICS, Ltd. 5
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "Global Facial ... http://photos.prnewswire.com/prnh/20130307/600769 ... the identification of individuals. Facial recognition system measures ... as nose, jaw edges, mouth, and the distance ...
(Date:12/11/2014)... PAUL, Minn. , Dec. 10, 2014 /PRNewswire/ ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ... Adding functional endpoints to toxicology studies ...
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 ... and collaboration catalyst that provides the connective tissue that ... by enabling them to easily share client-level information; earned ... Foundation to expand to organizations serving seniors aging in ... San Diego" partner on December 11 th 4-6p. ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... disease typhoid fever results from the ongoing battle between the ... the body. Prof. Dirk Bumann,s research group at the Biozentrum ... typhoid pathogen repeatedly manages to evade the host,s immune system. ... Host & Microbe ". Typhoid fever is a bacterial ...
... natural gas pipelines have been found under the streets of ... Boston University. A dozen of the leaks could have ... concentrations as high as 500,000 parts per million of natural ... which explosions can occur. Four months after phoning ...
... from the University of Toronto (U of T) have found ... an individual,s nutritional needs vary by blood type--is not valid. ... . , "Based on the data of 1,455 ... diet theory," said the senior author of the study, Dr. ...
Cached Biology News:Typhoid fever -- A race against time 25,900 natural gas leaks discovered under Washington, D.C. 25,900 natural gas leaks discovered under Washington, D.C. 3Popular blood type diet debunked 2
Mouse monoclonal [34B12] to Nop5p + Nop58p - Nucleolar Marker ( Abpromise for all tested applications)....
... the ultimate tool for investigating dynamic events ... previously have been limited at wavelengths longer ... not transmit in the deep UV. HORIBA ... introduces a filter-based confocal system (the DynaMic) ...
... bind specifically to Fc regions of many ... conjugates are commonly used as affinity adsorbents ... from serum, hybridoma ascites fluids, tissue culture ... are also commonly used to capture immune ...
... This quick (10 min) assay can ... non-fluorescent substrate, 10-acetyl-3,7-dihydroxyphenoxazine (ADHP). H2O2 oxidizes ADHP ... fluorescent product resorufin (excitation at 530-571 nm, ... catalyzed by peroxidase in a one-step, homogeneous, ...
Biology Products: