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Michael J. Fox Foundation Offers High-Quality LRRK2 Antibodies for PD Therapeutic Development
Date:3/23/2010

The Foundation's ongoing investment in critical research tools is made possible through the generous support of The Brin Wojcicki Foundation.

About LRRK2 and LRRK2 Antibodies

LRRK2 is a Parkinson's-implicated gene discovered in 2004 that is now believed to be the single greatest genetic contributor to the disease. While it is the focus of intensive research in the Parkinson's field, a major roadblock to the successful development of LRRK2-based therapies is the lack of high-quality LRRK2 antibodies. Antibodies are used by researchers to identify where proteins can be found in the body, how they behave in cells, and how to manipulate their activity. Despite numerous attempts by individual researchers, high-quality LRRK2 antibodies are rare and often difficult for labs to obtain.

In 2009 MJFF convened a LRRK2 Antibodies Working Group composed of academic and industry researchers with specific expertise in LRRK2. At the recommendation of this group, MJFF engaged a company specializing in antibody development, Epitomics, Inc., to generate several highly sensitive and specific LRRK2 antibodies in large amounts.


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SOURCE Michael J. Fox Foundation
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