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Metanomics Health and the Drug Safety Executive Council™ (DSEC) expand the scope of MetaMap®Tox
Date:3/7/2013

Needham, MA (PRWEB) March 07, 2013

Metanomics Health GmbH – a BASF Group Company and the Drug Safety Executive Council™ (DSEC™) will expand the evaluation of MetaMap®Tox – a new toxicological profiling tool for biopharmaceutical safety research. Metanomics Health is a BASF Group company and a leader in metabolite profiling. DSEC is an industry consortium focused on supporting the faster development of safer medicines, managed by Cambridge Healthtech Associates™ (CHA™).

Under the new agreement, MetaMap®Tox will be tested for its ability to provide early, reliable detection of cardiotoxicity, one of the major concerns in pharmaceutical drug development. In collaboration with several undisclosed global pharmaceutical partners, MetaMap®Tox will undergo an expanded validation phase, including blinded testing.

“Cardiovascular toxicity is a leading contributor to drug withdrawal and late-stage attrition. There is an urgent need for early detection of cardiotoxicity in pharmaceutical drug development,” said Dr. Ernie Bush, Scientific Director of the Technology Evaluation Consortium™ (TEC) collaborative projects for DSEC. “This project will help our pharmaceutical partners make important progress in their ability to more efficiently evaluate new chemical entities.”

MetaMap®Tox enables an early safety assessment of novel drug candidates by evaluating specific metabolomic patterns in vivo, leading to a better and earlier identification of potential safety risks of novel active pharmaceutical ingredients,
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