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Metamark and HistoRx Announce Licensing Agreement for AQUA® Technology
Date:12/20/2010

CAMBRIDGE, Mass. and BRANFORD, Conn., Dec. 20, 2010 /PRNewswire/ -- Metamark Genetics, Inc., a privately held oncology-focused molecular diagnostics company, and HistoRx, Inc., a diagnostics company developing tissue-based diagnostic solutions to advance individualized patient care, today announced a multi-year licensing agreement.  HistoRx has granted Metamark a worldwide license to the AQUA technology for the clinical commercialization of Metamark's proprietary MetamarkDx™ Prognostic Assays.  

For several years, Metamark has engaged HistoRx for research work in support of Metamark diagnostic assays based on HistoRx's proprietary AQUA technology.   The two companies have been working to achieve key validation milestones prior to finalizing this agreement.  Metamark's proprietary MetamarkDx Prognostic Assays will evaluate the molecular profile of an individual patient's tumor through quantitative expression analysis of Metamark's proprietary Prognosis Determinants™. This will enable the identification of those early stage cancers that are genetically hardwired for lethal spread, as well as those that are less aggressive, thus arming physicians with critical insight to be able to guide their patients towards more personalized treatment strategies.

The licensed portfolio includes assays performed using HistoRx's proprietary technology for analysis of fluorescent immunohistochemistry, enabling quantitative assessment of specific biomarkers for patients with certain solid tumors.  

"We are delighted to be working with HistoRx and are eager to develop and validate clinical diagnostics for key biomarkers using AQUA technology, and to ultimately commercialize them for the benefit of patients around the world," said Mark Straley, President and Chief Executive Officer of Metamark.  "Metamark's powerful Prognosis Determinants™ technology, and the multimarker assay panels developed from it, requires objec
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SOURCE HistoRx, Inc.; Metamark Genetics, Inc.
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