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Metabolic Solutions Development Company Receives $773,000 From the Alzheimer's Drug Discovery Foundation to Fund Phase 2a Trial
Date:7/6/2011

hat supported preclinical research, conducted in collaboration with Douglas Feinstein, Ph.D. of the Jesse Brown VA Medical Center and the University of Illinois at Chicago, which demonstrated positive effects of MSDC-0160 in a mouse model of Alzheimer's disease.

"We are very enthusiastic about MSDC's novel compound as a potential new treatment for Alzheimer's disease," said Howard Fillit, MD, ADDF's executive director. "Our ongoing relationship with the company further reinforces the ADDF's commitment to venture philanthropy as a catalyst for the acceleration of new drugs to prevent, treat and, ultimately, cure Alzheimer's disease."

MSDC-0160 also is currently being studied in patients with type 2 diabetes. A 90-day, Phase 2b study involving approximately 330 patients at 26 sites throughout the United States was launched in September 2010.

About Metabolic Solutions Development Company (MSDC)

Metabolic Solutions Development Company (www.msdrx.com) is a drug discovery and development company exploiting novel molecular targets to develop new therapies for metabolic diseases associated with altered mitochondrial function, especially insulin resistance and type 2 diabetes. The company has raised nearly $50 million in support of the development of its pioneer and lead products, MSDC-0160 (currently in Phase 2b) and MSDC-0602 (currently in Phase 2a), which are novel insulin sensitizers that selectively modulate mitochondrial control of certain metabolic-signaling and nutrient-sensing pathways resulting in improved insulin action without fluid retention or weight gain.  Founded in 2006 by former Upjohn Company researchers Jerry Colca, Ph.D. and Rolf Kletzien, Ph.D., MSDC is headquartered in Kalamazoo, Michigan.    

About the Alzheimer's Drug Discovery Foundation

The Alzheimer's Drug Discovery Foundation (ADDF) is the onl
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