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Metabolex Appoints Raymond Urbanski M.D., Ph.D. to Position of Chief Medical Officer
Date:10/20/2011

HAYWARD, Calif., Oct. 20, 2011 /PRNewswire/ -- Metabolex, Inc., a biopharmaceutical company focused on the discovery and development of proprietary new medicines for the treatment of metabolic diseases, announced today that Dr. Raymond Urbanski has joined the company as Chief Medical Officer.  Dr. Urbanski brings extensive clinical development experience to Metabolex, including expertise in all phases of clinical trial design and execution.

Dr. Urbanski was the Vice President and Medical Head of the Established Products Business Unit at Pfizer since 2008 which he built into a global business. From 2004-2008, he held various positions in the Pfizer Global Pharmaceutics Group.  He was the Vice President for Research and Development at Suntory Pharmaceutical, Inc. from 2001-2004 and held various positions at Aventis and AstraZeneca between 1998 and 2001. He received his Ph.D. in pharmacology and his M.D. from the University of Medicine and Dentistry of New Jersey.

"Ray is a great addition to our management team," said President and Chief Executive Officer Harold Van Wart, Ph.D. "Ray's leadership roles in well respected pharmaceutical companies, his experience in clinical development and his commercial insights will be critical for us as we advance our lead gout drug candidate arhalofenate into Phase 3 studies and ultimate commercialization. He will also be instrumental in helping the company chart the best course for its other two clinical assets – MBX-2982 and MBX-8025."

Metabolex has initiated three 28-day Phase 2b studies for arhalofenate in gout patients.  The first study is a randomized double-blind placebo-controlled study that will evaluate the safety and urate-lowering activity of 400 and 600 mg of arhalofenate used as mono-therapy.  Enrollment into this study of 60 patients with hyperuricemia and a diagnosis of gout has been completed.

Metabolex has also initiated Phase 2b studies in which arhalofenat
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SOURCE Metabolex, Inc.
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