“These findings broaden our view of therapeutic targets to include the host response,” he said. “The improvement in impaired and normal wound healing has significant clinical relevance for all wounds, chronic and acute.”
“This study indicates that signals within the wound bed may be activated after engraftment, suggesting that controlling mobilization is a key to success in future therapies,” said Anthony Atala, MD, Editor of Stem Cells Translational Medicine and director of the Wake Forest Institute for Regenerative Medicine.
Peterson and Shin are stem cell biologists at the Chicago Medical School, one of five schools and colleges at Rosalind Franklin University of Medicine and Science in North Chicago, IL, where Peterson directs the Center for Stem Cell and Regenerative Medicine. Their study was supported with funds from the U.S. Department of Energy, an American Diabetes Association Clinician Scientist Training Grant, and in part by an Intramural Award from Rosalind Franklin University of Medicine and Science.
The full article, “Human mesenchymal stem cell grafts enhance normal and impaired wound healing by recruiting existing endogenous tissue stem/progenitor cells,” can be accessed at http://www.StemCellsTM.com.
About STEM CELLS Translational Medicine: STEM CELLS TRANSLATIONAL MEDICINE (SCTM), published by AlphaMed Press, is a monthly peer-reviewed publication dedicated to significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices.
About AlphaMed Press: Established in 1983, AlphaMed Press with offices in Durham, NC, S
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