Navigation Links
Merrimack to Present Pre-Clinical Data on MM-121 and MM-111 at the 101st Annual Meeting of American Association for Cancer Research (AACR)
Date:4/17/2010

MM-121 studies in breast cancer models and xenograft response prediction. MM-111 breast cancer study in combination with trastuzumab.

Cambridge, MA (PRWEB) April 17, 2010 -- Merrimack Pharmaceuticals, Inc. announced today that it will present pre-clinical data on MM-121 and MM-111, the two lead candidates in the company’s pipeline of five novel cancer antibodies, at the 101st Annual Meeting of the American Association for Cancer Research (AACR) being held April 17 – 21, 2010, in Washington, D.C.

MM-121
Two posters will show pre-clinical data on MM-121, a monoclonal antibody designed to block signaling of the ErbB3 receptor. The ErbB receptor family has been known for years to have an impact on cancer signaling. Merrimack gained insight into the critical role of the ErbB3 receptor in cancer biology through the use of their Network Biology platform that led to the novel design of MM-121.

Poster 1806 shows pre-clinical data on MM-121’s efficacy as a single agent, and in combination with tamoxifen and paclitaxel, in ER+ and triple negative breast cancer studies.

Title: Efficacy of MM-121 in ER+ and triple negative breast cancer studies
Poster Session: Clinical Research 7
Number: 1806
Date/Time: Monday April 19, 2010 9:00 AM - 12:00 PM
Location: Exhibit Hall A-C, Poster Section 32 Permanent Abstract


MM-121
Poster 3756 shows pre-clinical data on efforts to derive a predictive biomarker signature that identifies tumors responsive to MM-121.

Title: Prediction of xenograft response to MM-121, an anti-ErbB3 inhibitor, using computational modeling and measurements of five biomarkers
Poster Session: Clinical Research 13
Number: 3756
Date/Time: Tuesday April 20, 2010 9:00 AM - 12:00 PM
Location: Exhibit Hall A-C, Poster Section 33


MM-111
MM-111 is a bispec
'/>"/>

Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Clet Niyikiza, Merrimack's Executive Vice President of Development, to Present at BioVisionAlexandria 2010
2. Merrimack Pharmaceuticals Promotes William Sullivan to Vice President of Finance
3. Merrimack Pharmaceuticals Recognized for Innovative Talent Management in HR Executive Magazine's ‘Best HR Ideas for 2010' Issue
4. Merrimack Pharmaceuticals Initiates Enrollment in Phase 1/2 Combination Study of MM-121 and Tarceva in Patients with Non-Small Cell Lung Cancer
5. Merrimack Pharmaceuticals Acquires Hermes Biosciences, Inc.
6. Merrimack Pharmaceuticals Names Clet Niyikiza, Ph.D. Senior Vice President, Development
7. Merrimack Pharmaceuticals Promotes Ulrik B. Nielsen, Ph.D. to Chief Scientific Officer and Edward J. Stewart to Senior Vice President of Business Development
8. Merrimack Pharmaceuticals Initiates Enrollment in a Phase 1 Study of MM-121, an ErbB3 Antagonist
9. Merrimack Pharmaceuticals Raises $60 Million in Private Financing
10. Merrimack Pharmaceuticals Announces the Addition of Robert Gay to its Board of Directors
11. Zimmer Holdings to Present at Barclays Capital 2010 Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... “Preparative & Process Chromatography Market by ... Solvents, Buffers, Valves, Guages, Seals), Accessories, Services, End ... to 2019” provides a detailed overview of the ... and strategies impacting the preparative and process chromatography ... the revenue and share analysis. , Full ...
(Date:12/24/2014)... On Friday, December 19, 2014, President ... and Continuing Resolution Appropriations Act of 2015, which ... eligible to receive funding through the Congressionally Directed ... of Defense (DoD). The Hydrocephalus Association (HA), working ... is celebrating this victory for the over 1 ...
(Date:12/24/2014)... 2014 The report expects global cell ... 2019. It also provides a carefully analyzed data about ... for the market. , Full Copy of Report @ ... global market for cell expansion will keep witnessing growth ... this growth to be driven by rapid technological advancements, ...
(Date:12/24/2014)... PharmaBoardroom,s new report, , ... available for free download , digs deep into this ... in the sector today. One area where ... in developing a homegrown pharmaceutical manufacturing base, even if the ... some way off. A cursory comparison with neighboring ...
Breaking Biology Technology:Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3
... California taxpayer and consumer rights group believes the U.S. ... the Wisconsin Alumni Research Foundation regarding its ... foundation said its recent $1 million jury reward in ... patents. , ,Representatives of the Foundation for Taxpayer ...
... Jim Doyle has signed into law Senate Bill 338, ... obstacles that stand in the way of University of ... researchers more quickly turn research ideas into potential business ... review whenever UW faculty and staff try to start ...
... capitalist in San Francisco or Boston, and youre on the verge ... Everything looks right: The management team is in place, the business ... ,But then a lawyer steps into the room, clears her throat ... law. Better not write that check, she says, until you learn ...
Cached Biology Technology:California group says ruling weakens WARF's stem cell patent 2California group says ruling weakens WARF's stem cell patent 3California group says ruling weakens WARF's stem cell patent 4Why repealing the shareholder wage lien law makes sense 2Why repealing the shareholder wage lien law makes sense 3
(Date:12/5/2014)... MOUNTAIN VIEW, Calif. , Dec. 4, 2014 ... and safety has boosted investments in new testing ... products has also given rise to a range ... driven by the requirements of Generation Y, which ... digital technologies. As a result, product development strategies ...
(Date:11/21/2014)... 2014 According to a new ... (Video, RFID, Access Control, Intrusion Detection, Parking Management, Under ... Component Service Geography - Global Forecasts to 2020", published ... to be around $25 Billion in 2014 and is ... a CAGR of 8.69%. Browse 116 market ...
(Date:11/18/2014)... 18, 2014  The Secure Identity & Biometrics ... jointly announce the formation of The Airport Entry ... Identity and Biometric Entry and Exit Solutions ... official support from BORDERPOL, the international non-profit organization ... provide expertise regarding border security, traveler and migration ...
Breaking Biology News(10 mins):Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
... WASHINGTON, D.C. (March 6, 2011) -- New findings from researchers ... Sick Children in Toronto may shed light on the mechanisms ... a critical aspect of cell signaling not well understood at ... of the macrophage protein CD36, a clustering-responsive class B scavenger ...
... MARCH 4, 2011 North and South Carolina have seen ... years. In North Carolina alone, swine production generates approximately a ... so many large-scale pig farms leads to the problem of ... the Carolinas is storing animal waste in anaerobic lagoons. They ...
... of Engineering researcher is seeking a new way to ... their voice. But this isn,t "The King,s Speech," the ... therapy to battle a stammer. Instead, Alexander Leonessa ( ... of stroke patients and others who have suffered paralysis ...
Cached Biology News:Environmental impact of animal waste 2Virginia Tech researcher seeks to use electrical stimulation to give voice to stroke patients 2Virginia Tech researcher seeks to use electrical stimulation to give voice to stroke patients 3
ANTI-HUMAN CYTOKINES, GROWTH FACTORS (polyclonal rabbit (or goat) antibodies) Human TARC - Biotin...
Rabbit polyclonal to Glutathione S Transferase alpha ( Abpromise for all tested applications). Antigen: Full length protein: Human Glutathione S Transferase alpha. Entrez GeneID: 2938 Swi...
Anti-Mouse IgM Heavy Chain:FITC, Clone LO-MM-9, Monoclonal Antibody...
Rabbit polyclonal to FOXJ2 ( Abpromise for all tested applications). entrezGeneID: 55810 SwissProtID: Q9P0K8...
Biology Products: