Navigation Links
Merrimack Pharmaceuticals To Present Preliminary Clinical Data For Novel Therapies Targeting Molecular Pathways In Advanced Cancers
Date:9/18/2012

CAMBRIDGE, Mass., Sept. 18, 2012 /PRNewswire/ -- Merrimack Pharmaceuticals, Inc. (NASDAQ: MACK) today announced that research evaluating two novel compounds for advanced cancers, including breast, ovarian, gastric and bladder, will be presented at the ESMO 2012 Congress (European Society for Medical Oncology ), Sept. 28 – Oct. 2 in Vienna, Austria. The medicines are some of the first therapies developed using Merrimack's proprietary scientific approach – Network Biology – focusing not on gene expression but on underlying cancer signals that trigger tumor growth.

"At Merrimack Pharmaceuticals, we believe the key to finding new treatment options for cancer is to start closer to the source of the problem – with signals in the cancer cell that turn specific processes on and off, triggering tumor growth and drug resistance," said Robert J. Mulroy, President and Chief Executive Officer, Merrimack Pharmaceuticals. "By charting and modeling these molecular pathways and signals, we can identify the most sensitive points from which to attack the cancer and then develop medicines and companion diagnostics to disrupt or slow tumor growth."

Therapy and Poster Overview:

  • MM-121 is a fully human monoclonal antibody that binds to ErbB3, a protein central to the development of drug resistance and tumor growth in numerous cancers, including ovarian, breast and lung tumors. It is designed to block the signal that allows ErbB3 to bind with other proteins and trigger cell growth and drug resistance.
    • A Phase 1 Study of the Anti-ErbB3 Antibody MM-121 in Combination with Weekly Paclitaxel in Patients with Advanced Gynecological and Breast Cancers (Abstract #: 974PD)
      • Presentation: Gynecological Cancers, Sunday, Sept. 30, 2012, 1:00PM – 2:00PM CET, Hall G
  • MM-111 is a bispecific antibody designed to target cancer cells that are characterized by overexpression of the ErbB2 (HER2) cell receptor. MM-111 is designed to uniquely address the tumor growth and survival signaling promoted by the ErbB2, ErbB3 and heregulin signaling complex.
    • A Phase 1 Study of MM-111; a Bispecific HER2/HER3 Antibody Fusion Protein, Combined with Multiple Treatment Regimens in Patients with Advanced HER2 Positive Solid Tumors (Abstract #: 496P)
      • Poster Session: Poster Presentation III, Monday, Oct. 1, 2012, 1:00PM – 2:00PM CET, Hall XL

About Merrimack Pharmaceuticals, Inc.

Merrimack Pharmaceuticals is a biopharmaceutical company discovering, developing and preparing to commercialize innovative medicines paired with companion diagnostics for the treatment of serious diseases, with an initial focus on cancer. Merrimack applies Network Biology, its proprietary systems biology-based approach to biomedical research, throughout the research and development process. Merrimack currently has five targeted therapeutic oncology candidates in clinical development.

Forward-Looking Statement

Any statements in this press release about future expectations, plans and prospects for Merrimack constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995, as amended. Actual results may differ materially from those indicated by such forward-looking statements. Merrimack anticipates that subsequent events and developments will cause its views to change. However, while Merrimack may elect to update these forward-looking statements at some point in the future, Merrimack specifically disclaims any obligation to do so.

Contact:
Kathleen Petrozzelli Gallagher, Merrimack, 617-441-1043, kgallagher@merrimackpharma.com

Liz Bryan, Spectrum, 202-955-6222, lbryan@spectrumscience.com


'/>"/>
SOURCE Merrimack Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Inovio Pharmaceuticals to Present at Noble Financial Life Sciences Conference
2. MD Anderson Cancer Center joins Actinium Pharmaceuticals (API) Multicenter Actimab-A Trial
3. Lexicon Pharmaceuticals To Present At The Morgan Stanley Global Healthcare Conference
4. Walgreens Joins with Ferring Pharmaceuticals Inc. to Offer Products and Resources to Women Facing Fertility Complications from Cancer Treatment
5. Isis Pharmaceuticals To Present At Two Upcoming Investor Conferences
6. Onyx Pharmaceuticals To Present At Upcoming Investor Conferences
7. Epigenomics, Present and Future Applications for Pharmaceuticals and Diagnostics: Twease.org
8. Inspiration Biopharmaceuticals Announces New Global Commercialization Agreements with Ipsen
9. Mangrove Partners Sends Letter to Stockholders of Nabi Biopharmaceuticals
10. MAP Pharmaceuticals to Present at Upcoming Investor Conferences
11. Avanir Pharmaceuticals Reports Fiscal 2012 Third Quarter Financial And Business Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Durham, NC (PRWEB) , ... June 23, 2016 , ... ... Odense University Hospital in Denmark detail how a patient who developed lymphedema after being ... (fat) tissue. The results could change the paradigm for dealing with this debilitating, frequent ...
(Date:6/23/2016)... , June 23, 2016  Blueprint Bio, a company ... to the medical community, has closed its Series A ... Nunez . "We have received a commitment ... capital we need to meet our current goals," stated ... us the runway to complete validation on the current ...
(Date:6/23/2016)... On Wednesday, June 22, 2016, the ... the Dow Jones Industrial Average edged 0.27% lower to finish ... 0.17%. Stock-Callers.com has initiated coverage on the following equities: Infinity ... NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ... ). Learn more about these stocks by accessing their free ...
(Date:6/23/2016)... ... 23, 2016 , ... Regulatory Compliance Associates® Inc. (RCA), a ... webinar on Performing Quality Investigations: Getting to Root Cause. This ... charge. , Incomplete investigations are still a major concern to the Regulatory Authorities ...
Breaking Biology Technology:
(Date:6/22/2016)... BETHESDA, Md. , June 22, 2016  The American ... by Trade Show Executive Magazine as one of ... Summit on May 25-27 at the Bellagio in ... based on the highest percentage of growth in each of ... number of exhibiting companies and number of attendees. The 2015 ...
(Date:6/16/2016)... , June 16, 2016 ... is expected to reach USD 1.83 billion by ... View Research, Inc. Technological proliferation and increasing demand ... are expected to drive the market growth. ... The development of advanced multimodal techniques ...
(Date:6/3/2016)... , June 3, 2016 ... Management) von Nepal ... und Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, ... führend in der Produktion und Implementierung von ... der Ausschreibung im Januar teilgenommen, aber Decatur ...
Breaking Biology News(10 mins):