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Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update
Date:11/10/2008

3100 has been generally well tolerated, with

no reports of serious adverse events deemed related to the drug.

-- Approximately 120 patients have been enrolled in the trial with

enrollment completed at doses up to 360 mg/day. A total of 73 patients

in the three lowest expanded dose groups (60, 150, and 240 mg/day) have

been followed for more than 24 weeks. Of these 73 patients, 31

patients (42 percent) have received MDV3100 for greater than 24 weeks.

Dose escalation in the trial is continuing; the 360 mg/day expansion

group is completely enrolled, dose escalation is in progress at 480

mg/day, and initial dosing at 600 mg/day has started. Thus far a

maximum tolerated dose (MTD) has not been reached.

-- Medivation expects to seek FDA agreement to begin a pivotal Phase 3

registration study in castration-resistant prostate cancer patients in

2009.

Third Quarter 2008 Financial Results

Medivation reported a net loss for the quarter ended September 30, 2008 of $20.5 million, or $0.68 per share, compared with a net loss of $9.4 million, or $0.34 per share, for the same period in 2007. For the nine months ended September 30, 2008, the net loss was $54.5 million, or $1.86 per share, compared with a net loss of $22.2 million, or $0.80 per share, for the same period in 2007.

Total operating expenses for the nine months ended September 30, 2008 were $20.6 million, compared with $9.8 million for the same period in 2007. The increase in operating expenses for the third quarter of 2008 compared with the same period in 2007 is primarily due to increased development costs associated with Dimebon and MDV3100.

For the nine months ended September 30, 2008, total operating expenses were $55.3 million, compared with total operating expenses of $23.7 million for the same period in 2007. These figures include non-cash stock-based compensation expense
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SOURCE Medivation, Inc.
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Related biology technology :

1. Medivation Announces Third Quarter 2008 Teleconference and Webcast on November 10, 2008
2. Medivation Announces Expiration of Hart-Scott-Rodino Waiting Period for Collaboration With Pfizer
3. Medivation Announces Presentation of 24-Week Clinical Data of MDV3100 in Castration-Resistant Prostate Cancer Patients
4. Medivation Receives Corporate Achievement Award From Huntingtons Disease Society of America
5. Medivation to Host Conference Call at 8:30 a.m. Eastern Time Tomorrow to Discuss Partnering Plans for Dimebon
6. Medivation Announces Participation in Upcoming Conferences
7. Medivation Reports Second Quarter 2008 Financial Results and Provides Corporate Update
8. Medivation Announces Second Quarter 2008 Teleconference and Webcast on August 11, 2008
9. Medivation Announces Presentation at the BMO Capital Markets 2008 Focus on Healthcare Conference on August 5
10. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients
11. Medivation Announces Senior Management Promotions
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