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Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update

ion upon the attainment of development and

regulatory milestones, plus additional undisclosed commercial milestone


-- Enrollment in CONNECTION, our confirmatory Phase 3 trial in

mild-to-moderate Alzheimer's disease, continues on track. All 30 of

our U.S. sites have been opened, and we expect the majority of our

ex-U.S. sites to be opened by the end of November. We expect to

complete enrollment of this trial in 2009.

-- Completed a randomized, double-blind safety and tolerability study of

combination therapy with Dimebon and donepezil (Aricept(R)) in patients

with Alzheimer's disease, which found the combination to be well

tolerated with no serious adverse events.

-- Plan to initiate new Phase 3 studies in 2009 to seek further

differentiation of Dimebon to include moderate-to-severe Alzheimer's

disease, adjunctive use with cholinesterase inhibitors, and

twelve-month efficacy.

-- Received a Corporate Achievement Award from the Huntington's Disease

Society of America (HDSA) for exemplifying leadership in the fight

against Huntington's disease and other neurodegenerative diseases.

-- Plan to initiate the next Huntington's disease efficacy study in 2009.

MDV3100: Drug candidate to treat castration-resistant prostate cancer

-- Presented data at the 20th EORTC-NCI-AACR Symposium on "Molecular

Targets and Cancer Therapeutics" from an ongoing open-label,

dose-escalation, U.S.-based Phase 1-2 clinical trial in prostate cancer

patients who have failed standard hormonal therapies. Results showed

encouraging and durable anti-tumor activity in the three expanded dose

groups tested thus far, as measured by prostate specific antigen (PSA)

declines, radiographic findings, circulating tumor cell (CTC) changes,

and time on treatment. MDV

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
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Related biology technology :

1. Medivation Announces Third Quarter 2008 Teleconference and Webcast on November 10, 2008
2. Medivation Announces Expiration of Hart-Scott-Rodino Waiting Period for Collaboration With Pfizer
3. Medivation Announces Presentation of 24-Week Clinical Data of MDV3100 in Castration-Resistant Prostate Cancer Patients
4. Medivation Receives Corporate Achievement Award From Huntingtons Disease Society of America
5. Medivation to Host Conference Call at 8:30 a.m. Eastern Time Tomorrow to Discuss Partnering Plans for Dimebon
6. Medivation Announces Participation in Upcoming Conferences
7. Medivation Reports Second Quarter 2008 Financial Results and Provides Corporate Update
8. Medivation Announces Second Quarter 2008 Teleconference and Webcast on August 11, 2008
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10. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients
11. Medivation Announces Senior Management Promotions
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