Navigation Links
Medivation Reports Fourth Quarter and Year-End 2008 Financial Results and Provides Corporate Update
Date:3/16/2009

we and Pfizer elect to pursue that option.
  • Plan to initiate enrollment next month in our Phase 3 CONCERT trial, a 12-month safety and efficacy study evaluating Dimebon in combination with donepezil (Aricept(R)) in approximately 1,000 patients with mild-to-moderate Alzheimer's disease.
  • Plan to initiate two additional Phase 3 studies in 2009 that will evaluate Dimebon in a total of approximately 1,100 patients with moderate-to-severe Alzheimer's disease.

    • Huntington's Disease

    • Held an end-of-Phase 2 meeting at which the U.S. Food and Drug Administration (FDA) informed us that we could begin a Phase 3 trial of Dimebon in patients with Huntington's disease using the Mini-Mental State Examination (MMSE) and the Clinician's Interview-based Impression of Change, plus caregiver input (CIBIC-plus) as co-primary endpoints. Discussions with the European regulators are ongoing. We expect to begin this study in 2009.
    • Presented the data from the Phase 2 trial of Dimebon in Huntington's disease patients at the 9th International Conference on Alzheimer's and Parkinson's Diseases (AD/PD) held last week. Results showed Dimebon to be well tolerated and to significantly improve cognition as measured by the MMSE.

    Mechanism of Action (MOA)

    • Presented new data at various medical conferences, including the recent AD/PD conference, that provide additional evidence that Dimebon potentially stabilizes and improves mitochondrial function in a way that prevents neuron death and dysfunction, a mechanism thought to be distinct from currently available Alzheimer's disease medications.
    • At AD/PD, we presented new research from the Karolinska Institutet, which quantified the impact of Dimebon on mitochondrial function. Responses were seen on mitochondria
      '/>"/>

    SOURCE Medivation, Inc.
    Copyright©2009 PR Newswire.
    All rights reserved

    0

    GOOD

    Page: 1 2 3 4 5 6 7 8

    Related biology technology :

    1. Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients
    2. Medivation Presents New Data on Dimebons Novel Mechanism of Action
    3. Medivation Announces Participation in RBC Capital Markets 2008 Healthcare Conference
    4. Medivation Reports Third Quarter 2008 Financial Results and Provides Corporate Update
    5. Medivation Announces Third Quarter 2008 Teleconference and Webcast on November 10, 2008
    6. Medivation Announces Expiration of Hart-Scott-Rodino Waiting Period for Collaboration With Pfizer
    7. Medivation Announces Presentation of 24-Week Clinical Data of MDV3100 in Castration-Resistant Prostate Cancer Patients
    8. Medivation Receives Corporate Achievement Award From Huntingtons Disease Society of America
    9. Medivation to Host Conference Call at 8:30 a.m. Eastern Time Tomorrow to Discuss Partnering Plans for Dimebon
    10. Medivation Announces Participation in Upcoming Conferences
    11. Medivation Reports Second Quarter 2008 Financial Results and Provides Corporate Update
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:5/21/2013)... Clinverse, Inc. , a ... trials, announced today it has formed a strategic ... ClinPay® FLS eClinical commerce platform aggregates data collected ... SpendMD ™, Aggregate Spend Solutions’ recently-launched flagship product, ... reporting transfer of value at investigator meetings or ...
    (Date:5/21/2013)... As the R&D sector becomes ... the industry to deliver better products, faster. Collaborations ... companies often means turning big ideas into reality, ... collaboration with Sensidose AB and Recipharm, is one ... to market sooner. The partnership resulted in the ...
    (Date:5/21/2013)... ROCKVILLE, Md. , May 21, 2013 /PRNewswire/ ... "Phase 1 study of margetuximab (MGAH22), an Fc-modified ... solid tumors expressing the HER2 oncoprotein," will be ... American Society of Clinical Oncology during the Developmental ... June 3 at 4:15 – 4:30 PM.  The ...
    (Date:5/21/2013)... Bed bugs have become so widespread in the past ... to chemical-based pesticides for help to completely get rid of ... solutions present, the company advised the public to kill ... According to My Cleaning Products, chemical-based pesticides are not as ... shared that the pests have already developed immunity to the ...
    Breaking Biology Technology:Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3The Development of an Innovative Microtablet Dosage Form, a Success Story: Live Webinar Hosted by Xtalks 2MacroGenics Announces Margetuximab (MGAH22) Phase 1 Data Presentation at ASCO; Initiates Phase 2 Clinical Study to Evaluate Activity of Margetuximab in Patients with Metastatic Breast Cancer 2MacroGenics Announces Margetuximab (MGAH22) Phase 1 Data Presentation at ASCO; Initiates Phase 2 Clinical Study to Evaluate Activity of Margetuximab in Patients with Metastatic Breast Cancer 3New Guide to Kill Bed Bugs Published by My Cleaning Products, Company Enumerates Non-Toxic Means to Clear the Pests 2New Guide to Kill Bed Bugs Published by My Cleaning Products, Company Enumerates Non-Toxic Means to Clear the Pests 3
    ... Ohio,s strengths in the polymer industry ... fields to spark biomedical innovation, COLUMBUS, Ohio, Nov. ... biomedical research, commercialization and innovation after the,recent launch of ... Ohio Business Development Coalition, the nonprofit,organization that markets the ...
    ... Medical Sciences, Providers of Inactivated Polio Vaccine (IPV) ... ... PARIS, November 12 Sanofi Pasteur, the,vaccines division of sanofi-aventis ... from Sanofi Pasteur for primary,immunization of all infants. The IPV ...
    ... getting smaller and smaller. And as hand-held devices from ... get more powerful, the race is on to develop memory ... on tiny formats. , Researchers at The University of Nottingham ... carbon nanotubes to create a cheap and compact memory cell ...
    Cached Biology Technology:Ohio Becoming Global Hub for Biomedical Research and Commercialization 2Ohio Becoming Global Hub for Biomedical Research and Commercialization 3Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 2Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 3Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 4Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 5Russia Chooses Inactivated Polio Vaccine from Sanofi Pasteur for Primary Immunization of all Infants 6Miniaturizing memory: Taking data storage to the molecular level 2
    (Date:5/22/2013)... working to improve durability in fuel cell powered ... have discovered links between electrode degradation processes and ... the effects of electrode degradation stressors in the ... lifetime. , The findings of the study, led ... latest in a long-term study at Burnaby-based Ballard ...
    (Date:5/22/2013)... (May 22, 2013)The omega 3 fatty acids in fish ... diseaseso much so that the American Heart Association currently ... week, particularly fatty varieties rich in omega 3s. However, ... mystery. In a new study, scientists led by Jason ... this phenomenon by providing evidence that fish oil might ...
    (Date:5/22/2013)... DNA can endanger the whole organism, as they may ... (LMU) in Munich now report how byproducts of respiration ... The DNA in our cells controls the form and ... instructions for this are encoded in the linear sequence ... adenine (A), cytosine (C), guanine (G) and thymine (T). ...
    Breaking Biology News(10 mins):Tests lead to doubling of fuel cell life 2Fish oil may help the heart beat mental stress 2DNA damage: The dark side of respiration 2
    ... CORVALLIS, Ore. As wolf populations grow in parts of ... value in aiding broader ecosystem recovery but a new ... could play an important role in helping to save other ... Bulletin, scientists suggest that a key factor in the Canada ...
    ... asthmatic children, on their exposure to molds or dampness in ... C has greater or smaller beneficial effect against asthma, according ... Proposals that vitamin C might be beneficial in the treatment ... from controlled trials have been conflicting., Drs Mohammed Al-Biltagi from ...
    ... the world,s strangest animals a unique fish that lives on ... has a rich and complex social life, a new study has ... arnoldorum ) has been detailed for the first time in research ... to colonise the land., The Pacific leaping blenny is a marine ...
    Cached Biology News:Wolves may aid recovery of Canada lynx, a threatened species 2Landlubber fish leap for love when tide is right 2
    RAT ANTI MOUSE TCR V BETA 7:RPE Immunogen: T-cell lymphoma TK1...
    ... Serum • Rhesus serum is collected from ... years of age. Available Anticoagulants: ... (Na) N-06: K2EDTA N-08: ... N-03: Alsevers N-05: ACD ...
    Porcine Serum US Origin 6 Months or Older...
    SEQUENASE PCR PRODUCT PRE-SEQU, 1 EA. Category: SEQUENASE....
    Biology Products: