Navigation Links
Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients
Date:4/14/2008

chief executive officer of Medivation. "The analysis of the association between PSA declines and clinical outcomes is ongoing. We look forward to providing additional results from this clinical trial at an upcoming medical conference."

The ongoing Phase 1-2 trial is an open-label U.S. study enrolling prostate cancer patients who have failed standard hormonal therapies. The study is currently planned to enroll patients in 4 dose-expansion cohorts. Of the 21 patients treated at the lowest expanded dose of 60 mg/day evaluated at three months, 43 percent showed a >50 percent decline in PSA levels from baseline. The study endpoints include safety, tolerability, pharmacokinetics, effects on serum PSA levels and disease progression.

Medivation expects to complete the study, and report final top-line results, in 2008. If these results are positive, Medivation expects to seek U.S. Food and Drug Administration (FDA) agreement to enter pivotal Phase 3 registration study in castration-resistant prostate cancer.

About Prostate Cancer

Prostate cancer is the most common non-skin cancer in the United States and the third most common cancer worldwide. More than 1 million men in the United States have prostate cancer. An estimated 186,320 new cases are expected to be diagnosed in 2008, and approximately 28,660 men are expected to die this year from the disease. Patients with castration-resistant (also known as hormone-refractory) prostate cancer have few treatment options and a poor prognosis.

About Medivation

Medivation, Inc. is a biopharmaceutical company with small molecule drugs in clinical development to treat three large, unmet medical needs -- Alzheimer's disease, Huntington's disease and castration-resistant (also known as hormone-refractory) prostate cancer. The Company's strategy is to identify promising product candidates, to develop them in a rapid, cost-effective manner, and to seek development and/or commercialization partners a
'/>"/>

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Medivation Announces Senior Management Promotions
2. Medivation Reports Year-End 2007 Financial Results and Pipeline Progress
3. Medivation Announces Participation in Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference
4. Medivation Selected as Founding Member of New NASDAQ(R) NeuroInsights(R) Neurotech Index
5. Boston Scientific Announces Japanese Approval of Heart Failure Lead
6. Vasogen Announces Implementation of Strategic Restructuring Plan
7. Cephalon Announces European Commission Approval of EFFENTORA for the Treatment of Breakthrough Cancer Pain
8. EXL Announces Appointment of Rembert de Villa as Head of Transformation Services
9. Botaneco Announces Launch of Second Generation Oleosome Product
10. YM BIOSCIENCES ANNOUNCES PRESENTATIONS FOR TWO OF ITS ANTI-CANCER DRUGS AT AACR ANNUAL MEETING
11. Signalife Announces Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... , Cambridge Semantics, the leading provider of Smart ... announced its participation in the 2014 Big Data Leaders ... provide semantic linkage and meaning to Big Data to ... diverse data. Ben Szekely, vice president and founding engineer ... sciences data lake” and an approach for collecting and ...
(Date:10/1/2014)... BETHESDA, Md. , Oct. 1, 2014 /PRNewswire/ ... committed to the fostering and monetization of intellectual ... Spherix,s litigation against VTech and Uniden in the ... Texas has been rescheduled ... scheduled for October 2, 2014.  The Court Order ...
(Date:10/1/2014)... Irvine, CA (PRWEB) September 30, 2014 ... for user-friendly, cost-effective tools to address sales, training ... PMG has developed innovative mobile applications to ... studies, outlining the agency’s latest customized mobile app ... http://www.studiopmg.com/work . , In partnership with Toyota, ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 The U.S. ... to Southern Illinois University Edwardsville as part of the ... initiative. The funding is co-administered by the Department of ... Biden, Secretary of Labor Thomas E. Perez and Secretary ... million in job-driven training grants to nearly 270 colleges ...
Breaking Biology Technology:Cambridge Semantics to Present ‘A Useful Approach to Big Data’ at 2014 Big Data Leaders Forum 2Markman Hearing Date for VTech and Uniden Litigation Now Set for November 10, 2014 2Digital Agency Studio PMG Launches New Case Studies on Website 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 3U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 4
... Esker Software, worldwide leader in ... Esker Fax and VSI-FAX(R) product ... Notes 3.0. This new solution ... communicate more efficiently, effectively, and ...
... often encounter certain genes, chromosomal regions or entire ... CloneSmart technology was designed specifically to eliminate many ... individual gene or a complete genome. The technology ... clone sequences that are difficult to clone with ...
... Information Networks Corporation, a leading Midwest provider of data ... it has been selected by Microsoft as a featured ... Studio .NET 2003 Launch. , , ,Scheduled for ... inMilwaukee, Wisconsin, Berbee will speak in depth about addressing ...
Cached Biology Technology:Molecular Cloning Systems Gets Distributor 2
(Date:9/30/2014)... Evidence of the environmental effects of moorland burning is ... the subject, with the aim of relieving tensions on ... , The EMBER (Effects of Moorland Burning on the ... burning on moorland, which is practised predominantly to support ... impacts on peat hydrology, peat chemistry and physical properties, ...
(Date:9/30/2014)... monkeys have captured the popular attention of both children ... cycle -- sold as dehydrated eggs, these tiny brine ... than a tank of salt water. , Physicists, ... zooplankton, brine shrimp vertically migrate in large groups in ... surface at night and retreating deeper during the day. ...
(Date:9/30/2014)... Medicine reports positive results of a phase 1 ... of lung cancer marked by rearrangement of the gene ... advanced non-small cell lung cancer testing positive for ROS1 ... 3 complete responses and 33 partial responses. Median progression-free ... to resume its growth after being slowed by treatment ...
Breaking Biology News(10 mins):Grouse moor burning causes widespread environmental changes 2Laser-guided sea monkeys show how zooplankton migrations may affect global ocean currents 2NEJM: Crizotinib effective in Phase 1 trial against ROS1 lung cancer 2
... at the Smithsonian Institution and the Hawaii Institute of ... have created the first frozen bank for Hawaiian corals ... to preserve their diversity in Hawaii. Mary Hagedorn, an ... with the Smithsonian Conservation Biology Institute, leads the laboratory ...
... treatment, also brings debilitating side effects such as nausea, liver ... a new way to deliver this life-saving therapy to cancer ... has been invented by Dr. Dan Peer of Tel ... Center for Nano Science and Nano Technology together with Prof. ...
... More than 120 sturgeon and paddlefish scientists and enthusiasts from ... 2 in Bozeman and at Chico Hot Springs in Montana. ... North American Chapter of the World Sturgeon Conservation Society and ... in North America. The meeting will begin in Bozeman, ...
Cached Biology News:Smithsonian scientists help create first frozen repository for Hawaiian coral 2A cluster bomb for cancer care 2
Homo sapiens MEP50 protein, mRNA...
Mouse H60 Allophycocyanin MAb (Clone 205326) ENTREZ GeneID: 15101...
RAB32, member RAS oncogene family, mRNA (cDNA clone MGC:13500 IMAGE:4280407), complete cds...
EDTA, 0.5 M solution, 100 ml. Ethylene diaminetetraacetic acid.Sterile, nuclease-free. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Biology Products: