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Medivation Announces New Positive Efficacy Data From Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients
Date:2/25/2009

king doses of 600 mg/day and 360 mg/day. Both patients were taking concomitant medications that can cause seizures. A possible but unwitnessed seizure was reported in a patient taking a dose of 480 mg/day.

"We are pleased to continue to see concordance of data across endpoints -- CTC changes, PSA declines, radiographic findings and time on treatment," said David Hung, M.D., president and chief executive officer of Medivation. "We continue to move forward with clinical development of MDV3100 and expect to seek U.S. Food and Drug Administration approval to advance to a pivotal Phase 3 registration study this year."

The new MDV3100 efficacy and safety data will be presented in a poster session on Friday, February 27 at 11:45 a.m. Eastern Time at the American Society of Clinical Oncology's (ASCO) 2009 Genitourinary Cancers Symposium in Orlando, Fla.

Teleconference/Webcast Details

Dr. Scher will participate in a teleconference and webcast of a slide presentation today at 4:30 p.m. Eastern Time. He will discuss the new MDV3100 data and the recent research regarding the association between changes in the number of CTCs and the prediction of survival and response to treatment in patients with advanced prostate cancer.

To participate in the live call by telephone, please dial 877-719-9810 from the U.S. or +1-719-325-4785 internationally. Individuals interested in listening to the live call via webcast may do so by visiting http://www.medivation.com. A slide presentation that will accompany today's teleconference can be accessed via the Web by accessing the webcast and will also be posted as a PDF next to the event listing in the Investor section of the Medivation website. A replay of the webcast will be available on the Company's website for 30 days.

About Prostate Cancer and MDV3100

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SOURCE Medivation, Inc.
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