Navigation Links
Medicago discovers breakthrough method of preparing plant derived recombinant proteins and VLPs and files two PCT patent applications
Date:9/22/2010

QUEBEC CITY, Sept. 22 /PRNewswire-FirstCall/ - Medicago Inc. (TSX: MDG), a biotechnology company focused on developing highly effective and affordable vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced it has filed two international patent applications under the Patent Cooperation Treaty (PCT) that broadly cover new methods of preparing plant-derived recombinant proteins and VLPs.

"The extraction and purification of recombinant proteins and complex structures such as VLPs from plant cell impurities has been a major impediment to the development of our industry since its early days. Current methods rely on mechanical breakdown of plant biomass to separate recombinant proteins and VLPs from plant cells. Unfortunately these methods also frees plant impurities from the plant cell, which render downstream purification more costly and complex." said Louis Vézina, Chief Scientific Officer of Medicago. "We have discovered and filed patent applications for a new method of biochemical degradation that releases recombinant proteins and/or VLPs in the extract and eliminates most plant-originating impurities in one single-step which greatly simplifies subsequent purification steps."

"These new patent applications will enhance the company's IP position, and establish our competitive advantage with respect to the development of VLPs and other recombinant proteins in plants. We have successfully applied our process to a broad range of VLPs and recombinant proteins such as antibodies," said Andy Sheldon, President and CEO of Medicago. "Our new purification process will reduce cost, allow for a simpler regulatory process, and provide easier technology transfer for potential licensees. We hold all intellectual property rights related to our purification process and believe our innovative method is a key technology for the future of our industry."

About Medicago

Medicago is committed to provide highly effective and affordable vaccines based on proprietary Virus-Like Particle (VLP) and manufacturing technologies. Medicago is developing VLP vaccines to protect against H5N1 pandemic influenza, using a transient expression system which produces recombinant vaccine antigens in non-transgenic plants. This technology has potential to offer advantages of speed and cost over competitive technologies. It could deliver a vaccine for testing in about a month after the identification and reception of genetic sequences from a pandemic strain. This production time frame has the potential to allow vaccination of the population before the first wave of a pandemic strikes and to supply large volumes of vaccine antigens to the world market. Additional information about Medicago is available at www.medicago.com.

Forward Looking Statements

This news release includes certain forward-looking statements that are based upon current expectations, which involve risks and uncertainties associated with Medicago's business and the environment in which the business operates. Any statements contained herein that are not statements of historical facts may be deemed to be forward-looking, including those identified by the expressions "anticipate", "believe", "plan", "estimate", "expect", "intend", and similar expressions to the extent they relate to Medicago or its management. The forward-looking statements are not historical facts, but reflect Medicago's current expectations regarding future results or events. These forward-looking statements are subject to a number of risks and uncertainties that could cause actual results or events to differ materially from current expectations, including the matters discussed under "Risks Factors and Uncertainties" in Medicago's Annual Information Form filed on March 24, 2010 with the regulatory authorities. Medicago assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those reflected in the forward-looking statements.


'/>"/>
SOURCE Medicago Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Medicago named in Presidential report on meeting the challenges of pandemic influenza
2. Medicago reports positive Phase I results for its avian flu pandemic vaccine
3. Medicago to present at the U.S. Department of Health and Human Services Global Health Security Initiative Workshop
4. Medicago awarded contract by the U.S. Army to explore applications of its plant-based technology in renewable energy
5. Medicago begins human clinical testing with its avian flu pandemic vaccine
6. Medicago receives regulatory approval to begin human clinical testing with its avian flu pandemic vaccine
7. Medicagos H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose
8. Medicago succesfully expresses VLP antigen for A H1N1 strain
9. Medicago initiates work on Swine Flu strain
10. deCODE Discovers Major Genetic Risk Factor for the Most Common Form of Glaucoma
11. deCODE Discovers Genetic Risk Factor Linking Susceptibility to Four Major Vascular Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/3/2016)... , ... February 03, 2016 , ... ... Linux and Unix visualization solutions today announced the addition of a powerful “Session ... users to see the current state of the remote Linux desktop or other ...
(Date:2/3/2016)... Therapeutics, Inc., today announced the closing of a $6 million ... total of $10.25 million in Series A funding based on ... was led by existing investor The Kraft Group of ... Lear Corporation and Highland Consumer Partners, as well as existing ... Sackler , MD, with Summer Road, LLC; Erin Donohue ...
(Date:2/3/2016)... , ... February 03, 2016 , ... ... to aid in the rapid development and ongoing quality control of molecular assays ... outbreak is extremely high,” Dr. Gregory R. Chiklis, President and CEO of ZeptoMetrix, ...
(Date:2/3/2016)... ... 03, 2016 , ... Marktech Optoelectronics, a leading supplier of ... epi wafers based in Latham, New York, offers a wide variety of ... Si and InGaAs PIN photodiodes. But it is Marktech's newly enhanced capability to ...
Breaking Biology Technology:
(Date:2/2/2016)... NEW YORK , Feb. 2, 2016 ... healthcare facilities are primarily focused on medical ... that measure point-of-care parameters. Wearable devices that ... a user,s freedom of movement are being ... sensors for human biomedical signal acquisition coupled ...
(Date:2/2/2016)... Feb. 2, 2016   Parabon NanoLabs ... U.S. Army Research Office and the Defense Forensics ... sensitivity of the company,s Snapshot Kinship Inference ... and, more generally, defense-related DNA forensics.  Although Snapshot ... (predicting appearance and ancestry from DNA evidence), it ...
(Date:2/1/2016)... , Feb. 1, 2016  Wocket® smart wallet ( www.wocketwallet.com ) announces ... personality, Joey Fatone . Las Vegas , ... --> Las Vegas , where Joey appeared ... The new video ad was filmed at the Consumer Electronics Show ... the Wocket booth to meet and greet fans. ...
Breaking Biology News(10 mins):