Navigation Links
Medgenics Announces Encouraging Preliminary Data For Phase I/II Clinical Trial of EPODURE In Renal Anemia
Date:11/3/2008

Data will be presented during Renal Week 2008,November 4th through 9th in Philadelphia, Pennsylvania

MISGAV, Israel and LONDON, Nov. 3 /PRNewswire-FirstCall/ -- Medgenics (AIM: MEDG), is pleased to announce encouraging preliminary data for its Phase I/II clinical trial.

The landmark Phase I/II clinical trial of Medgenics' EPODURE Biopump, for providing sustained treatment of anemia in subjects with chronic kidney disease, is underway. The current trial is designed to assess the safety and efficacy of the EPODURE Biopump in providing sustained elevation of hemoglobin by delivering sufficient supplemental amounts of the protein erythropoietin (EPO) for 3-6 months. Each subject will be monitored for 6 months after the EPODURE implantation. Further applications of the Biopump platform technology will be developed and tested from 2009 onwards.

The first month's data from the on-going Phase I/II trial has now been collected from the initial two anemic, chronic kidney disease subjects receiving the lowest dose in this dose escalating study. One subject received 2 and the other 3 Biopumps, reflecting the respective number needed to provide the intended low daily EPO dose of 18-25 IU/kg/day in each subject. The hemoglobin levels of each of these subjects have risen and remain within the target range of between 10 and 12 grams per deciliter for a month, with no adverse effects reported or observed, other than minor localized bruising typically associated with skin biopsy and implant. The 10-12 grams per decilitre range is what is recommended for such patients to treat their anemia. As the trial progresses these subjects will continue to be monitored, additional subjects will be enrolled and further data will be reported as key milestones are achieved. The Directors expect to commence testing on further subjects before the end of 2008.

The Directors are encouraged by the fact that, although the trials are at an early stage, the elevated hemog
'/>"/>

SOURCE Medgenics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. YM BIOSCIENCES ANNOUNCES COMPLIANCE WITH AIM RULE 26
3. Emisphere Technologies, Inc. Announces Pricing of Registered Direct Offering
4. BioLife Solutions Announces Exclusive CryoStor(TM) Supply Agreement With the New England Cryogenic Center, Inc.
5. Carrington Announces Nasdaq Communication; Prepares for Shares to Be Quoted on the OTC Bulletin Board and Pink Sheets
6. China Kangtai Cactus Biotech Files 2nd Quarter 2007 10QSB and Announces Unaudited Quarterly Results
7. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
8. Advanced Life Sciences Announces Receipt of Nasdaq Staff Letter
9. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
10. Angiotech announces additional diameters of sutures to further expand its Quill(TM) SRS PDO product line
11. CNS Response Announces Fiscal Third Quarter 2007 Results

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/1/2009).... 1 /PRNewswire-Asia/ -- Shanghai ChemPartner, as ...China-based Contract Research,Organization (CRO), ...e,Technology Fast 50 China, ranking 3rd on the lis...ina. The award is a testament to ChemPartner,s out...08. , The results of the 2009 Deloitte Te...
(Date:12/1/2009)...l., Dec. 1 Prairie Heart Institute...was recently awarded two statuettes at the first-e... York City. The CLIO Healthcare Awards recognizes ...re advertising industry and is an extension of the...wards competitions for advertising, design and int...
(Date:12/1/2009)...rprise level storage is now available to small and...ng the bank. , (PRWEB) De....com ), a medical imaging software company, annou...torage service. The PacsDrive service enables smal...ly archive medical imaging in compliance with HIPA...
(Date:12/1/2009)...ruent Software agrees to migrate their Microsoft D...lients) to Synergy Business Solutions to maintain ...e, WA (PRWEB) December 1, 2009 -- Synergy Business...rosoft Dynamics SL practice of Congruent Software,...move was necessary due to a change in Congruent So...
Breaking Biology Technology:Shanghai ChemPartner Ranks 3rd among 2009 Deloitte Technology Fast 50 China Winning Companies 2Shanghai ChemPartner Ranks 3rd among 2009 Deloitte Technology Fast 50 China Winning Companies 3Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 2PacsDrive Announces Low Cost Medical Imaging Storage Service, Seeks to Alter Status Quo in Health Care IT 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 3
...in Technology Council has published the first-ever... The 24-page publication highlights the states res...reation, quality of life, key contacts and the I-Q...polis-St. Paul. , ,The Wisconsin Technology Netwo...s: Wisconsin The Smart Choice, over the next few ...
...e Wisconsin Technology Network sat down with Tom S...ouncil , to discuss the basic tenets of the organi...g forth to help Wisconsins technology space grow. ...: What are the biggest challenges the Wisconsin Te... greatest accomplishments? , ,Tom Still: The grea...
...e proud , ,So how many boards can you break with...ny projects can you juggle at one time? Even more ...ey the ones that will best improve your organizati...6 Sigma might be for you! , ,6 Sigma (6σ) is...on customer requirements. Sigma refers to the Gree...
Other Biology Technology:Life Science: From Chicago to the Twin Cities: All tech roads lead to Wisconsin 2Life Science: From Chicago to the Twin Cities: All tech roads lead to Wisconsin 3WTN exclusive interview with Tom Still, Wisconsin Technology Council - Part 2 2WTN exclusive interview with Tom Still, Wisconsin Technology Council - Part 2 3WTN exclusive interview with Tom Still, Wisconsin Technology Council - Part 2 4Part 6 Project Performance Get on the path to continuous improvement 2Part 6 Project Performance Get on the path to continuous improvement 3Part 6 Project Performance Get on the path to continuous improvement 4
(Date:12/2/2009)..., REDWOOD SHORES, Calif. and PALM HARBOR, Fla., ...elligence Corporation ("CIC") (OTC Bulletin Board:... solutions for business process automation in the ... biometric signature verification and Docubase Sys...ectronic Document Management (EDM) software provid...
(Date:12/2/2009)... PhD student at the University of Southampton,s Sc...onal Oceanography Centre, Southampton (NOCS) has f...ll from the deep sea. , Hall discovered the new ...onal Museum of Natural History in Washington. Expl...ng crabs include some of the largest crustaceans c...
(Date:12/1/2009)...UNNYVALE, Calif., Dec. 1 GestureTe...ease 3.0 - a turnkey, portable, plug and play inte... exhibits, entertainment and touring promotions. G...patents in camera-enabled gesture recognition tech...ntertainment systems. ,, Guaranteed for quality...
Breaking Biology News(10 mins):CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 2CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 3CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 4King crab family bigger than ever 2GestureTek Unveils The CUBE V3 Portable, Plug and Play Interactive Projection Display System for Advertising and Exhibits 2Eli Lilly 26 Company and ScinoPharm Taiwan Ltd Announce Settlement of Gemcitabine Litigation 13272 1Eli Lilly 26 Company and ScinoPharm Taiwan Ltd Announce Settlement of Gemcitabine Litigation 13272 2Obama White House Can Save 243 7 Trillion and Extend Lifespan 29+ Years Predicts Revolutionary A4M Healthcare Plan 53184 1Obama White House Can Save 243 7 Trillion and Extend Lifespan 29+ Years Predicts Revolutionary A4M Healthcare Plan 53184 2New Custom Hybrid Planetary Gearbox Series from NMB 53182 1New Custom Hybrid Planetary Gearbox Series from NMB 53182 2
...colonial tuco-tuco fascinates biologists because i...has so little genetic diversity that the slightest...ped it off the face of the earth long ago. Yet the...to survive for thousands of years in the harsh cli...complex social structure that,s unique among the m...
... or other shape, neurons in various areas of the b...ts of that shape, almost instantaneously fitting t... the individual then "sees" and understands, resea... team from the university,s Zanvyl Krieger Mind/Br...cess in detail in a recent issue of the journal Ne...
...ges for patients but is very difficult for the sur...sterdam, Joris Jaspers has developed two instrumen...r than with existing surgical robotics. Jaspers is...lft University of Technology. , Endoscopic operati...or the patient and give a better cosmetic result t...
Other Biology News:Ancient DNA provides clues to the evolution of social behavior 2Ancient DNA provides clues to the evolution of social behavior 3Ancient DNA provides clues to the evolution of social behavior 4In the mind's eye: How the brain makes a whole out of parts 2Cheaper and simpler keyhole surgery 2
.... ELISA.Specific for total MMP-3: Recognizes proMM...activity with MMP-1, -2, -9. Range: 3.75-120 ng/ml...ll culture supernatant, serum, plasma and tissue s...gory: Drug Screening & Cellular Assays, Assays . S...
FractionPREP Cell Fractionation Kit from BioVision
Self Closing Forceps from Applied Biosystems
Petri Dish Perfusion Chamber Insert from AutoMate Scientific, Inc
Biology Products: