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Medarex Receives Milestone Payment for Submission of Regulatory Application Requesting Approval of Golimumab (CNTO 148) in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Date:3/20/2008

PRINCETON, N.J., March 20 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX) today announced that it has received a milestone payment of an undisclosed amount from its licensing partner, Centocor, Inc., for the submission of a Marketing Authorization Application to the European Medicines Agency requesting approval of golimumab (CNTO 148) for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

Golimumab is a human anti-TNF monoclonal antibody that was generated by Medarex's UltiMAb Human Antibody Development System. Medarex may receive future milestone payments and royalties should this product candidate progress to commercialization and achieve commercial sales.

"We are excited by this regulatory filing for approval of a fully human antibody developed by Medarex's technology, and we are pleased by the advancements that Centocor continues to make with these antibodies," said Howard H. Pien, President and CEO of Medarex. "We have seen the accomplishment of a number of development milestones for UltiMAb antibodies -- both by our partners and by Medarex -- and look ahead to similar accomplishments that we believe will lead to important medicines to address underserved medical needs."

About Medarex

Medarex is a biopharmaceutical company focused on the discovery, development and potential commercialization of fully human antibody-based therapeutics to treat life-threatening and debilitating diseases, including cancer, inflammation, autoimmune disorders and infectious diseases. Medarex applies its UltiMAb(R) technology and product development and clinical manufacturing experience to generate, support and potentially commercialize a broad range of fully human antibody product cand
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SOURCE Medarex, Inc.
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