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Technology enhances biological activity (regenerative potential) of stem cells and accelerates development of proprietary enhanced therapeutics
GAITHERSBURG, Md., Feb. 17 /PRNewswire-USNewswire/ -- MaxCyte announces today the introduction of its GT(TM) Flow Transfection System at the 4th Annual Stem Cell Summit to be held in New York, NY. The MaxCyte GT(TM) Flow Transfection System is a validated, scalable technology for customizing the biological activity of cells for therapeutic use. This system, which is supported by a US FDA Master File, enables rapid and efficient transfection of any primary cell or cell line with >90% cell viability following loading with a broad range of molecules (proteins, drugs, plasmids, mRNA, miRNA, and siRNA) or combinations thereof, at volumes up to tens of billion cells, processed in under 30 minutes. The MaxCyte GT(TM) Flow Transfection System enables consistent cGMP-compliant cell modification in a closed-system for clinical/commercial scale manufacturing. Appropriate for either cGMP facility or point-of-care use, the GT(TM) Flow Transfection System allows cost-effective delivery with both autologous and allogeneic cellular therapies, customized for enhanced efficacy.
"The MaxCyte GT(TM) Flow Transfection System addresses two of the primary challenges hindering acceleration of effective stem cell therapies. It enables design and development of stem cell products modified to allow for improved regenerative responses and permits robust, automated, cost-effective, cGMP and regulatory-compliant product manufacturing," says Dr. Madhusudan Peshwa, Executive Vice President of Cellular Therapies at MaxCyte. "Such reduction in efficacy and delivery risk in the early-stages of product development can significantly reduce cost, accelerate development, and enhance effectiveness, while providing for novel Intellectual Property around such engineered cell therapy and stem cell products."
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