Navigation Links
Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver
Date:11/17/2011

HUNTINGTON, W.Va. Recent studies conducted at Marshall University have demonstrated that nanoparticles of cerium oxide -- common diesel fuel additives used to increase the fuel efficiency of automobile engines -- can travel from the lungs to the liver and that this process is associated with liver damage.

The data in the study by Dr. Eric R. Blough and his colleagues at Marshall's Center for Diagnostic Nanosystems indicate there is a dose-dependent increase in the concentration of cerium in the liver of animals that had been exposed to the nanoparticles, which are only about 1/40,000 times as large as the width of a human hair. These increases in cerium were associated with elevations of liver enzymes in the blood and histological evidence consistent with liver damage. The research was published in the Oct. 13 issue of the peer-reviewed research journal International Journal of Nanomedicine.

Cerium oxide is widely used as a polishing agent for glass mirrors, television tubes and ophthalmic lenses. Cerium oxide nanoparticles are used in the automobile industry to increase fuel efficiency and reduce particulate emissions. Some studies have found that cerium oxide nanoparticles may also be capable of acting as antioxidants, leading researchers to suggest these particles may also be useful for the treatment of cardiovascular disease, neurodegenerative disease and radiation-induced tissue damage.

Blough, the center's director and an associate professor in the university's Department of Biological Sciences, said, "Given the ever-increasing use of nanomaterials in industry and in the products we buy, it is becoming increasingly important to understand if these substances may be harmful. To our knowledge, this is the first report to evaluate if inhaled cerium oxide nanoparticles exhibit toxic effects in the liver."

Dr. Siva K. Nalabotu, the study's lead author and a Ph.D. student in Blough's lab, said, "The potential effect
'/>"/>

Contact: Ginny Painter
ginny.painter@marshall.edu
304-746-1964
Marshall University Research Corporation
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Marshall Edwards CEO to Present at JMP Securities Healthcare Conference
2. Marshall Edwards CEO to Present at Lazard Capital Markets Healthcare Conference
3. Novogen and Marshall Edwards Sign Asset Purchase Agreement
4. Marshall Edwards to Report new Data on Mitochondrial Inhibitor Program at American Association for Cancer Research Annual Meeting
5. The American Ceramic Society selects Marshall, Niihara as 2011 Distinguish Life Members
6. Marshall Edwards Appoints Healthcare Investment Banking Veteran Charles Baltic to Board of Directors
7. InNexus Biotechnology Announces Launch of Large Scale Primate Study of DXL625
8. RAND study finds increase in piracy and terrorism at sea
9. Merrimack Pharmaceuticals Initiates Enrollment in a Phase 1 Study of MM-121, an ErbB3 Antagonist
10. Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure
11. Logical Therapeutics Inc. Announces Results of Phase 1b Clinical Study of its Naproxen Prodrug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Hills, NY (PRWEB) August 29, 2014 ... Burnt Hills Veterinary Hospital are seeking candidates to participate ... dogs with osteoarthritis. The ultimate goal of this ... donor stem cells into one or two arthritically affected ... treated joints. , Candidates for the current investigational ...
(Date:8/29/2014)... Boston, MA, San Antonio, TX (PRWEB) August 29, ... audited, ISO 9001:2008 and ISO 13485:2003 certified, GAMP® ... it has been awarded an international Phase II ... patients with non-Hodgkin’s lymphoma. , Throughout this trial, ... services including, but not limited to, protocol and ...
(Date:8/28/2014)... “This kit has an improved extraction efficiency and provides ... ppb,” said Mark Tess, PhD, Mycotoxin Product Manager for Charm ... and USDA-GIPSA inspection agencies that have a need to detect ... in a matter of minutes with nothing but our equipment ... and grain before accepting it, but they no longer have ...
(Date:8/28/2014)... Willow Grove, PA (PRWEB) August 28, 2014 ... talent, and create a culture that will allow individuals ... that are becoming increasingly important for employers looking to ... life science industries are embracing this trend, as the ... the fabric of a company, which will have real ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... GAITHERSBURG, Md., Nov. 12 MaxCyte, Inc.,the pioneer ... it will be hosting a live discussion with ... assays for drug discovery.,The discussion is open to ... on,Thursday, November 13th from 2:00-3:00EST., One of ...
... Surgery Institute Is ... in Moscow, MOSCOW, Nov. 12 A Vermont eye ... he implanted the,Crystalens HD into a 49 year old Russian ... Randolph, Vermont performed the surgery at the,Ninth International Conference on ...
... Recommendations, BETHLEHEM, Pa., Nov. 12 ... Marketing, Infusion Systems Division and Helen,Chang, PharmD, ... Braun Medical,Inc. (B. Braun), a global leader ... B. Braun at the Institute for Safe ...
Cached Biology Technology:MaxCyte Hosts Live Discussion with Industry Experts on the Challenges in Developing Cell-Based Screening Assays for Drug Discovery 2Vermont Surgeon Implants First Accommodating Crystalens in Russia 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 3
(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... Society of Human Genetics from October 18 22, ... meant to promote the entry of students, post doctorates ... the basic science community and to encourage the participation ... Genetics. This year MARC conferred 16 awards totaling ...
(Date:8/28/2014)... MD FASEB MARC (Maximizing Access to Research ... for the Genetics Society of America,s 27th Annual ... October 3, 2014 in Pacific Grove, California. ... of students, post doctorates and scientists from underrepresented ... community and to encourage the participation of young ...
(Date:8/28/2014)... Aug. 28, 2014  Privacy Advocate and Senior Staff ... Lynch , joins the lineup of biometric and mobile ... Biometrics UnPlugged Executive Summit in Tampa, Florida ... Previously announced speakers include Steven Rahman, Director, Technology and Strategy ... at Experian. The theme of this year,s event is ...
Breaking Biology News(10 mins):Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2
... Cells trying to keep pace with constantly changing environmental ... their genomic integrity and allowing enough genetic flexibility to ... at the Stowers Institute for Medical Research were able ... unstable, readily acquiring or losing whole chromosomes to enable ...
... today finds that tropical vegetation contains 21 percent more ... remote sensing and field data, scientists from Woods Hole Research ... able to produce the first "wall-to-wall" map (with a spatial ... of forests, shrublands, and savannas in the tropics of Africa, ...
... of rare, endemic species in the Central Andes remain ... climate change, according to a Duke University-led international study. ... particularly vulnerable to changes in the environment or climate. ... percent of the areas with high numbers of these ...
Cached Biology News:That which does not kill yeast makes it stronger 2That which does not kill yeast makes it stronger 3The good news about carbon storage in tropical vegetation 2The good news about carbon storage in tropical vegetation 380 percent of 'irreplaceable' habitats in Andes unprotected 2
... choice of PDMS Stamps (3 PDMS micropatterned ... micron squares or 100 um x 10 ... lines, 3 PDMS nano-patterned stamps with depth ... pitch of 400 nm, or 3 PDMS ...
Request Info...
RECOMBINANT EQUINE IL-4 Product Type: Recombinant Protein...
Request Info...
Biology Products: