Ganaxolone is a synthetic neurosteroid and derivative of the naturally occurring neuromodulator, allopregnanolone. It is being investigated as a first in class treatment for epilepsy. Ganaxolone has been administered to more than 950 healthy adult volunteers and patients in more than 35 Phase 1 and Phase 2 studies. Early epilepsy studies involved more than 100 patients and generated data supportive of the efficacy and safety of ganaxolone in the treatment of both children and adults suffering from refractory forms of epilepsy (patients who continue to have seizures despite taking multiple anticonvulsant drugs).
Marinus has successfully developed several proprietary formulations of ganaxolone.
About Marinus Pharmaceuticals
Marinus Pharmaceuticals, Inc. is a specialty pharmaceutical company dedicated to the reformulation, development, and commercialization of novel drugs to treat serious neurological, psychiatric, and pain disorders. Marinus Pharmaceuticals is located in Branford, Conn. Its investors include Domain Associates, Canaan Partners, Sofinnova Ventures and Foundation Medical Partners. For additional information, please visit the Company's Web site at http://www.marinuspharma.com/XQUOT;" target="_new">www.marinuspharma.com.
About Domain Associates
Founded in 1985, Domain Associates, L.L.C. is a venture capital firm with an exclusive focus on life sciences. With $2 billion of capital under management, Domain is headquartered in Princeton, NJ with a second office in San Diego, CA. Domain's three major investment segments are pharmaceuticals, specialty pharmaceuticals, and medical devices
|SOURCE Marinus Pharmaceuticals, Inc.|
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