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Marinus Pharmaceuticals Appoints John Krayacich as President and Chief Executive Officer
Date:8/5/2008

sing compounds through clinical development and closer to commercialization," said Mr. Krayacich. "I have committed my career to the development of novel therapies that address unmet patient needs and I'm excited about the innovative candidates in the Marinus pipeline."

About Marinus Pharmaceuticals

Marinus Pharmaceuticals is a privately held specialty pharmaceutical company that is dedicated to the identification, development, and commercialization of novel drugs to treat serious neurological, psychiatric and pain disorders. Its lead compound, ganaxolone, is a synthetic analog of the neurosteroid allopregnanolone (3a,5a-P), a metabolite of progesterone. It is currently being investigated in a Phase IIb clinical trial as a potential treatment of epilepsy in children (infantile spasms) and complex partial seizures in adults. Chelerythrine is currently in pre-clinical development for the treatment of bipolar disorder and the cognitive deficits of schizophrenia. Marinus' investors include Domain Associates, Canaan Partners, Sofinnova Ventures and Foundation Medical Partners. For additional information, please visit http://www.marinuspharma.com.

About Domain Associates

Domain Associates, LLC is a venture capital firm focused on health care product opportunities including biopharmaceuticals, medical devices and related businesses. Over its 23 year history, Domain has been involved in the creation of over 200 companies. Its latest venture capital fund is Domain Partners VII, L.P., which is capitalized at $700 million. Domain is located in Princeton, NJ and in San Diego, CA. For more information, please visit http://www.domainvc.com.

About Canaan Partners Healthcare

Canaan Partners invests in visionary entrepreneurs and provides them the networks, insights and operational guidance required to build high-performance technolog
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