Navigation Links
Making blood-sucking deadly for mosquitoes
Date:7/18/2011

Mosquitoes die soon after a blood meal if certain protein components are experimentally disrupted, a team of biochemists at the University of Arizona has discovered.

The approach could be used as an additional strategy in the worldwide effort to curb mosquito-borne diseases like dengue fever, yellow fever and malaria.

When the researchers blocked a cellular process known as vesicle transport, on which the mosquitoes rely to release digestive enzymes into the gut among other functions, it caused the affected animals to die within two days of blood feeding.

"The idea behind our research is this: If we can kill the mosquito after she bites the first person, she won't be able to bite and infect a second," said Roger Miesfeld, a professor in the UA's department of chemistry and biochemistry, who led the research project.

"We do this by blocking the mosquito's ability to digest its blood meal," said Miesfeld, also a member of the UA's BIO5 Institute.

The research team's findings were recently published in Proceedings of the National Academy of Sciences, or PNAS.

"During a blood meal, a mosquito ingests its body weight in blood. It's the equivalent of a 125-pound human consuming a 12-gallon smoothie made from 25 pounds of hamburger meat plus a half pound of butter and two tablespoons of sugar," Miesfeld said.

Miesfeld and the research team had previously shown that the blood feeding process poses a huge metabolic challenge to the female mosquito.

"By disrupting any number of biochemical processes needed to fully utilize the blood meal, the mosquito has a very difficult time completing the egg production cycle," he added.

To maintain their bodily needs, the insects rely on sugary nectar from flowers, but when the time to make eggs comes, they need large amounts of protein. Only female mosquitoes bite and feed on the blood of humans or warm-blooded animals.

If a
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related biology technology :

1. Bayer CropScience Releases Video About Making Science Make Sense Program At Durham Performance Learning Center
2. NASA is making hot, way cool
3. Penn physicists develop scalable method for making graphene
4. Thought Leaders in Europe and US Address Challenges to Making Rare Diseases a Global Public Health Priority
5. Making a point
6. Helix BioPharma Completes Definitive GLP Toxicology Studies With L-DOS47 and is Making Final Preparations for its Planned Phase I/II Clinical Study IND/CTA Submissions
7. Graphene 2.0: A new approach to making a unique material
8. New Report Finds A Brain Health Revolution in the Making, Driven by Digital Technology and Neuroplasticity Research
9. OnychoLase Laser Nail Centers Making a Global Impact, By Bringing Western Medicine To The East
10. Wine-making yeast shows promise for bioethanol production
11. A little less force: Making atomic force microscopy work for cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Making blood-sucking deadly for mosquitoes 
(Date:12/19/2014)... Dec. 18, 2014   ISN has released ... Performance Indicators publication series. With data aggregated ... reported in 2013 within its online contractor management platform, ... key performance indicator (KPI) statistics. The ... publication is available in two industry specific ...
(Date:12/17/2014)... Based on the revenues gained ... market is dominated by four major players contributing ... These players include GE Healthcare (U.K.), Siemens AG ... , Full Report Copy at http://www.marketsandmarkets.com/Market-Reports/surgical-imaging-market-210534462.html ... be attributed to its strong product portfolio, which ...
(Date:12/17/2014)... N.J. (PRWEB) December 17, 2014 ... (Euronext: IPN; ADR: IPSEY), today announced ... (referred to as Somatuline®) was approved by the ... treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in adult ... advanced or metastatic disease to improve progression-free survival ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 Xeno ... Excellence following its most recent COLA inspection. Xeno ... COLA, a national healthcare accreditation organization. Accreditation is ... of quality in day-to-day operations, demonstrate continued accuracy ... a rigorous on-site laboratory survey. , ...
Breaking Biology Technology:ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 8Xeno Diagnostics Receives 3rd Award for Laboratory Excellence 2
... Shamir,Optical Industry Ltd. (Nasdaq: SHMR ) ("Shamir"), ... the progressive ophthalmic lens,market, announced today that its ... an aggregate amount of US$ 4.0 million (approximately ... representative rate of,exchange), or approximately US$ 0.243 (approximately ...
... The American Cancer Society Estimates Approximately 20,000 Patients are ... Diagnosed With Brain Cancer Each Year in the ... January 14, Rosetta Genomics, Ltd. (Nasdaq: ROSG ), ... today it has signed a collaboration agreement with the ...
... Bio-Based Technologies to ... Meet Growing Global Demand, ... named Nicholas C. Fanandakis group vice president - DuPont Applied,BioSciences. ... efforts to commercialize a range of bio-based,products and technologies to ...
Cached Biology Technology:Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 2Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 3Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer 2Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer 3Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer 4DuPont Names Nicholas Fanandakis as Group Vice President - DuPont Applied BioSciences 2
(Date:12/10/2014)... DUBLIN , Dec. 08, 2014 Research ... announced the addition of the "Biometrics Market ... http://photos.prnewswire.com/prnh/20130307/600769 ... for projects such as rural banking and upgradation ... major trends witnessed in the market. Besides the ...
(Date:12/5/2014)... MOUNTAIN VIEW, Calif. , Dec. 4, 2014 ... and safety has boosted investments in new testing ... products has also given rise to a range ... driven by the requirements of Generation Y, which ... digital technologies. As a result, product development strategies ...
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a leading ... that its DigitalPersona ® Pro Enterprise software ... been deployed throughout First Bank branch locations in ... South Carolina and Virginia. First Bank, a ... Southern Pines, North Carolina , selected the ...
Breaking Biology News(10 mins):Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3
... Dana-Farber Cancer Institute (Dana-Farber), Burnham Institute for Medical ... and Prevention (CDC) have reported the identification of ... range of influenza A viruses, including avian influenza ... some seasonal influenza viruses. These antibodies have the ...
... BKYI) today announced plans to release fourth quarter 2008 financial results on ... the release, BIO-key has scheduled a conference call, which will be broadcast ... Eastern Time., What: ... ...
... species, known scientifically as Diporeia , is,related to ... the Great Lakes, say NOAA scientists. As invasive mussel ... many aquatic species have steadily and unilaterally declined. ... Laboratory published,this week in Freshwater Biology documents ...
Cached Biology News:Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses 2Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses 3BIO-key(R) Announces Fourth Quarter and 2008 Year-End Earnings Release and Conference Call Schedule 2
Sequencing and primer design rolled into one. Just give us your clone and a reference sequence, and we'll do the rest. Single-strand or double-strand coverage. Guaranteed results....
...
Anti-Wnt-2 Polyclonal Antibody Description: 100 g purified goat polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blot/IP/IHC. Research Focus: signal transduction Storage...
... microplate coating using advanced automated high throughput microplate processing equipment ... can also accommodate virtually any lot size of the following ... 8 and 12 well strips, ... 384 well microplate, ...
Biology Products: