Navigation Links
Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy
Date:11/11/2008

REYKJAVIK, Iceland, Nov. 11 /PRNewswire-FirstCall/ -- In a presentation today at the American Heart Association Scientific Sessions 2008, clinicians and researchers from Baylor College of Medicine have presented data from the Atherosclerosis Risk in Communities (ARIC) study, demonstrating that measuring the genetic risk factor on chromosome 9p21 detected by the deCODE MI(TM) test complements traditional risk factors to improve the assessment of individual risk of future coronary heart disease (CHD). This information can be used to more accurately assess target cholesterol levels and to inform lipid-modifying therapy recommendations.

Last year, deCODE discovered single-letter variations in the human genome (SNPs) on chromosome 9p21 that increase risk of heart attack, and launched its deCODE MI(TM) reference laboratory test to enable clinicians to measure this risk factor as part of their efforts to provide the best preventive strategies for their patients. In the study today, the Baylor team and colleagues from other academic institutions analyzed the clinical utility of testing for the 9p21 risk factor by adding it to a range of standard CHD risk factors followed by ARIC, a major, NIH-funded prospective study of cardiovascular disease and care begun in 1987. Through an analysis of more than 10,000 ARIC participants of European descent for whom 9p21 status was known, the study found that knowing the 9p21 risk made the assessment of individual risk more accurate and resulted in the reclassification from one risk category to another of a significant proportion of the overall cohort. The impact was most pronounced in the categories of intermediate risk, in which individuals were estimated to be at a 5-10% risk of CHD in the next ten years, and intermediate-high, with individuals at an estimated 10 -20% 10-year CHD risk. In these categories, 19% and 17% of people, respectively, were shifted to a different risk category as a result of integrating their 9p21
'/>"/>

SOURCE deCODE genetics
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Dow AgroSciences and Exelixis Plant Sciences Announce Major Research Collaboration, Asset Purchase to Advance Gene Discovery and Validation
2. Weil Gotshal Wins Major Victory for Applera; Secures Summary Judgment Invalidating Three Patents
3. Radius Grants Major Pharmaceutical Company Exclusive Option to License BA058 for Osteoporosis
4. Genzyme Begins Major Expansion of Boston Manufacturing Facility
5. International Atomic Energy Agency and National Foundation for Cancer Research Launch Major Initiative to Improve Cancer Prevention and Treatments in Developing Countries
6. Forest Laboratories Lexapro and Generics-Dominated Fluoxetine Lead First-Line Therapy in the Treatment for Major Depression
7. Updated Drug Development Scrip Report Responds to the Pharma Industrys Major Changes
8. National Surgical Hospitals Acquires Majority Share of Houston-Area Surgery Center
9. Agendia Acquires Rights to the Discovery of a Major Drug Resistance Mechanism in Breast Cancer Potentially Leading to a Herceptin(R) Sensitivity Test
10. Bioponic Phytoceuticals to Roll Out Multiple Products to 1,000 Major Health Food Stores in the Western United States
11. SPO Medical Announces Major Sales Milestone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... ... solutions, today announced its GHS Label Guide . To align chemical container ... (GHS), this guide includes explanations of label components, an example of an accurate ...
(Date:7/29/2015)... , July 29, 2015  Indivior PLC (LON: INDV) ... naloxone nasal spray was accepted and received Priority Review ... the treatment of opioid overdose. This naloxone nasal spray ... formulated for optimal absorption into the nasal mucosa. 1 ... training so individuals may be better equipped to help ...
(Date:7/29/2015)... ... July 29, 2015 , ... Finding gooey or crusty material in ... Although there are a considerable number of terms in popular use to describe it, ... is a mixture of mucus, blood cells, skin cells and dust, but until now ...
(Date:7/29/2015)... ... July 29, 2015 , ... Rainbow Scientific, Inc. ... announces the availability of BI’s line of human mesenchymal stem cell (hMSC) differentiation ... differentiation media offer a complete system for multipotency evaluation of hMSCs and reliable ...
Breaking Biology Technology:Brady Announces a New GHS Label Guide 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 3Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 4Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 5What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 2What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 4Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 2Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 3
... in Lille, France. This four-year-old conference draws nearly ... power of technology. As the lead speaker on a ... Social Conditions, I was eager, frankly, to dispense with ... hear from and debate my fellow panelists. , ,We ...
... Vehicles in Wisconsin plans to close all its offices on ... The new system, which has been in development for the ... searches faster and add newer programming languages. Employee training will ... day. , ,The existing system has been in place since ...
... of Wisconsins Department of Commerce, said on Friday that he would ... in the law firm Quarles & Bradys Milwaukee office. , ,Nettles ... years. He will be returning to the firm he worked at ... from Governor Doyle as a leader, a boss, and a friend, ...
Cached Biology Technology:Achieving digital solidarity 2Achieving digital solidarity 3Achieving digital solidarity 4Secretary Nettles leaving Commerce for law practice 2Secretary Nettles leaving Commerce for law practice 3
(Date:6/30/2015)... , June 30, 2015 Genisphere ... as CEO to help further develop Genisphere,s therapeutics capabilities ... partnering experience, having spent much of the last 25 ... Amgen, Baxter Bioscience, and Johnson & Johnson. Tom started ... Technology and Biotech Corporate Finance. He graduated from Dartmouth ...
(Date:6/25/2015)... SALT LAKE CITY , June 25, 2015 /PRNewswire/ ... the first steps toward a healthier, happier life. That,s ... app is designed to do. The cutting-edge, portable health ... and offers real-life solutions to help improve your lifestyle ... Sellers Association awards dinner and gala Wednesday night, USANA,s ...
(Date:6/24/2015)... June 24, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced that Sharp has selected its ... authentication for its latest flagship smartphone device, the ... 200 million shipments of its fingerprint ID sensor ... strength, scalability and leadership in the biometrics market ...
Breaking Biology News(10 mins):Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3@USANAinc's Personalized Nutrition Program Wins Industry Innovation Award 2Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2
... famous for its health benefits. But now scientists ... to produce medicines for several autoimmune and inflammatory ... the open access journal BMC Biotechnology . ... European research organizations have participated in the study ...
... MARCH 19 Ten prominent journalists from the United ... for the fifth annual TempletonCambridge Journalism Fellowships in Science ... a program of research and scholarship at the University ... announced today by the New York office of the ...
... Johns Hopkins engineers have invented a method that could ... break free from neighboring tissue, an "escape" that can ... The new lab-on-a-chip, described in the March issue of ... better cancer therapies. "Studying cell detachment at the ...
Cached Biology News:Tobacco makes medicine 2Fifth annual Templeton-Cambridge fellowships awarded to 10 noted journalists 2Fifth annual Templeton-Cambridge fellowships awarded to 10 noted journalists 3Fifth annual Templeton-Cambridge fellowships awarded to 10 noted journalists 4Lab-on-a-chip homes in on how cancer cells break free 2Lab-on-a-chip homes in on how cancer cells break free 3
DALT GRADIENT MAKER,230V, 1 EA. Category: 2D DALT Systems....
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
Rat whole blood (Sprague-Dawley, averaging 7-8 weeks of age, either sex) is collected at the time of slaughter and refrigerated within 6 hours, and processed and frozen within 24 hours. The serum is ...
... mutS and ES1301 mutS are mismatch repair ... these strains prevents repair of the newly ... mutation efficiencies and making them helpful in ... Sites II Mutagenesis Systems. Both ES1301 and ...
Biology Products: