Navigation Links
MacroGenics Receives NIH Grant Funding of $9.8M for Three Projects; Funding Further Advances DART Platform and Infectious Disease Portfolio
Date:7/15/2010

ROCKVILLE, Md., July 15 /PRNewswire/ -- MacroGenics, Inc, a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, today announced that the National Institutes of Health (NIH) has awarded the company three new grants representing total funding of $9.8 million.  These grants will help MacroGenics further advance its Dual-Affinity Re-Targeting (DART), or bispecific antibody scaffold platform, as well as its portfolio of infectious disease product candidates.  The first of three recently awarded NIH grants will fund preclinical IND-enabling activities related to MacroGenics' Inflammation DART.  This DART specifically targets B lymphocytes with the potential to treat a broad range of autoimmune diseases including lupus, rheumatoid arthritis, multiple sclerosis and other disorders.

MacroGenics was awarded two additional NIH grants related to infectious disease pathogens.  These grants, both of which fall under NIH's "Partnerships for Biodefense Viral Pathogens," cover research and development activities to create an antibody-based therapy for Chikungunya Virus and a DART-based pan-Dengue Virus immunotherapeutic for prophylaxis and treatment of Dengue Virus.  Both viruses are insect-borne and transmitted to humans by virus-carrying mosquitoes.  Dr. Michael Diamond at Washington University in St. Louis developed the Chikungunya and Dengue antibodies and is the grantee for the Chikungunya Virus award; MacroGenics is the sub-recipient.

MacroGenics also announced today the publication of two articles related to its DART platform.  These articles appeared in the July 2010 iss
'/>"/>

SOURCE MacroGenics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. MacroGenics Raises $25M in Series D-2 Financing
2. MacroGenics Appoints New Vice President of Business Development
3. Paulo F. Costa Joins MacroGenics Board of Directors
4. MacroGenics Announces the Initiation of a Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Monoclonal Antibody MGAWN1 in Subjects with Suspected Central Nervous System Infection Due to West Nile Virus
5. Medicsight Receives Brazilian State Food and Drug Administration Approval for ColonCAD Software
6. Angiotech receives CE Mark approval of HemoStream(TM) Chronic Dialysis Catheter
7. SGX - Lilly Merger Offer Receives Positive Opinions From Proxy Advisory Firms
8. CV Therapeutics Receives European Approval for the Brand Name Ranexa(R)
9. XTL Biopharmaceuticals Receives Notice of Non-Compliance with Nasdaq Marketplace Rule Due to Changes in Board Composition
10. BMP Sunstone Receives Production License from the SFDA to Manufacture and Market Pediatric Multivitamin Granules in the PRC
11. Biotest Diagnostics Receives FDA Clearance for Full Line of Traditional Blood Bank Reagents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... Gene Specific siRNA Controls , ... in siRNA , research or you ... convenience of the Silencer gene specific siRNA , ... contains 50 g of ready-to-use chemically synthesized and gel , ...
... , experiment depends ... expression vehicles (plasmids, PCR fragments) into cells. Many , ... reagents to deliver ... cells. The choice of reagent and the conditions under which it , ...
... Fluorescence activated cell sorting (FACS) is a , ... , individual cells using fluorescent probes that bind specifically ... is commonly used to collect , cells of a ... , Figure 1.Linear Amplification from 1-1000 Cells. ...
Cached Biology Technology:Control Your siRNA Research 2Control Your siRNA Research 3Choose the Right Transfection Agent for Your RNAi Experiment 2Choose the Right Transfection Agent for Your RNAi Experiment 3Choose the Right Transfection Agent for Your RNAi Experiment 4Choose the Right Transfection Agent for Your RNAi Experiment 5Choose the Right Transfection Agent for Your RNAi Experiment 6Choose the Right Transfection Agent for Your RNAi Experiment 7Cells-to-cDNA II Using FACS Sorted Cells 2
(Date:4/16/2014)... A research group composed of Dr. Martin Prechtl, Leo ... Department of Chemistry has discovered a new method of ... hydrogen from liquids is of particular interest when it ... project, entitled "Selective and mild hydrogen production using water ... Nature Communications . , Among other applications, the ...
(Date:4/15/2014)... Space Flight Center in Greenbelt, Md., is home ... support staff. At Goddard, some of the most ... and some of that cutting-edge innovation has earned ... The Swedish Society for Anthropology and Geography awards ... person who has shown excellence in the fields ...
(Date:4/15/2014)... succeeded in visualizing the movement within plants of ... to drought. The achievement will allow researchers to ... helps plants respond to drought and other environmental ... atmosphere,s carbon dioxide, or CO2, concentration., A paper ... issue of the scientific journal eLife ...
Breaking Biology News(10 mins):Goddard scientist receives Vega Medal from King of Sweden 2Biologists develop nanosensors to visualize movements and distribution of plant hormone 2
... finger as hard as you can against the surface. Now ... follow the ticking clock. Now faster. Now faster." These ... casts doubt on old ideas about mechanisms to control hand ... manual dexterity is so vulnerable to aging and disease, and ...
... developed salt-tolerant plants using a new type of genetic modification ... The research team based at the University of ... GM technique to contain salt in parts of the plant ... which means the results of this research could impact on ...
... 7, 2009) -- The Wildlife Conservation Society (WCS) announced today ... of the Amazon in Brazil. The monkey is related to ... their distinctively marked backs. The newly described distinct subspecies ... the state of Amazonas in northwestern Brazil. The discovery was ...
Cached Biology News:1-finger exercise reveals unexpected limits to dexterity 21-finger exercise reveals unexpected limits to dexterity 3Scientists closer to developing salt-tolerant crops 2New monkey discovered in Brazil 2
Request Info...
... Freezer Inventory Storage Racks for Standard ... to fit all makes and models ... Made of high quality stainless steel ... fiberboard, stainless steel or plastic boxes. ...
Immunogen: Recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Chlorine-36, 3.7 MBq, 100 uCi. 0.1-0.3 HCl.< 111 MBq/g Cl, < 3 mCi/g Cl.Dispensed to order. Please inquire for alternative pack sizes. Category: Radiochemicals &Radiation Safety, Radiochemicals....
Biology Products: