Navigation Links
MacroGenics Announces the Initiation of a Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Monoclonal Antibody MGAWN1 in Subjects with Suspected Central Nervous System Infection Due to West Nile Virus
Date:7/13/2009

supportive care. Therefore, a therapy that neutralizes the virus and could possibly reduce or prevent complications associated with West Nile Neuroinvasive Disease would represent a significant advancement for these patients."

About MGAWN1

MGAWN1 is a humanized monoclonal antibody that specifically recognizes the envelope (E) protein of WNV. MGAWN1 exhibits potent neutralizing and fusion-inhibitory activity against WNV in laboratory studies conducted in vitro and in vivo. MGAWN1 has a specific activity that is orders of magnitude higher than that of an intravenous immune globulin (IVIG) product when tested in laboratory studies.

About West Nile Virus

West Nile Virus has widespread prevalence throughout the U.S. http://www.cdc.gov/ncidod/dvbid/westnile/Mapsactivity/surv&control08Maps.htm) and other parts of North America. Approximately 20% of humans infected with WNV experience West Nile Feverwith clinical symptoms that include fever, headache, body aches, skin rash and swollen lymph glands. In approximately 1% of human infections, WNV enters the brain and causes severe, life-threatening neuroinvasive disease in the form of encephalitis, meningitis or acute flaccid paralysis. West Nile Neuroinvasive Disease (WNND) is associated with significant morbidity, and long-term neurological effects are common among survivors.

Since 1999, there have been more than 28,000 cases of confirmed symptomatic WNV infection in the U.S., which include more than 11,000 WNND cases and more than 1,100 deaths. In 2008, 1,356 cases of WNV infection were reported to the Centers for Disease Control and Prevention (CDC) for the year with 44 of these cases resulting in death. WNV is now the most common cause of epidemic viral encephalitis in the U.S., and it wil
'/>"/>

SOURCE MacroGenics, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Paulo F. Costa Joins MacroGenics Board of Directors
2. MacroGenics Appoints New Vice President of Business Development
3. MacroGenics Raises $25M in Series D-2 Financing
4. MacroGenics Acquires Raven Biotechnologies
5. Jeffrey H. Buchalter Joins MacroGenics Board of Directors as Chairman
6. China-Biotics, Inc. Announces Conference Call to Discuss Fourth Quarter and Full Year 2009 Financial Results
7. Mirixa Corporation Announces Key New Hires
8. Harvest Technologies Announces Completion of Patient Enrollment in its 60 Patient Clinical Trial in India Using Autologous Adult Stem Cells to Treat Patients With Non-Reconstructable Critical Limb Ischemia
9. Amylin Pharmaceuticals Announces Positive Results from Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment for Obesity
10. Cornerstone Therapeutics Inc. Announces Record Date and Meeting Date for Special Meeting of Stockholders for Vote with Respect to Charter Amendments
11. DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2015)...   Tamir Biotechnology , a leading developer of ... Ebola antiviral therapy program. Clinical Progress ... being evaluated and considered by a number of clinicians ... the first quarter of 2015, the company participated in ... Evaluation of Potential Treatments and Vaccines For Ebola In ...
(Date:4/30/2015)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), an ... has commenced an underwritten public offering of its common ... a 30-day option to purchase up to an additional ... in the public offering. The offering is subject to ... to whether or when the offering may be completed, ...
(Date:4/30/2015)... ALEXANDRIA, Va. , April 30, 2015 ... provides senior debt to life sciences and healthcare services ... senior secured term loan agreement with Celula, Inc., a ... diagnosing major diseases, enabling better patient care and improved ... continue the development and expand the commercialization of its ...
(Date:4/30/2015)... April 30, 2015 Biodata, producer ... with integrated protocols and specimen management systems, and ... and consulting services for life science research, announce ... Labguru’s newest feature: chemical structure and reaction support. ... for biologists, bio-chemists, and more, the integration of ...
Breaking Biology Technology:Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3Oxford Finance Provides $10 Million Debt Financing to Celula 2Labguru Integrates ChemAxon's Marvin JS, to Enhance Functionality for Chemists 2
... Company Provides Revised Timing on Interim Celgosivir Viral Kinetics Study ... ... DIEGO, Oct. 31 /PRNewswire-FirstCall/ - MIGENIX Inc.,(TSX: MGI; OTC: MGIFF), a clinical-stage ... & Renshaw 9th Annual,Healthcare Conference being held at the New York Palace ...
... Corporation,an orthopedic implants company focused on silicon nitride ... Drug Administration,has granted 510(k) marketing clearance to Amedica,s ... system combines features aimed at making,cervical fixation procedures ... is intended for anterior screw fixation at,the C2 ...
... on high tech development, opportunities for business growth, ... report shows Ohio,colleges and universities increased academic research ... more money than ever into high,technology R&D sectors ... support for high tech research, development and,commercialization, especially ...
Cached Biology Technology:MIGENIX to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 2MIGENIX to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 3Ohio Academic Institutions Increase Research and Development Investments 2Ohio Academic Institutions Increase Research and Development Investments 3
(Date:4/17/2015)... BURNABY, Canada , April 17, 2015 /PRNewswire/ ... projects, growing security concerns, and technological advancement to ... Arabia until 2020   ... " Saudi Arabia Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric ... is projected to register growth at CAGR ...
(Date:4/14/2015)... OXFORD, Conn. , April 14, 2015 ... "Company"), a biometric authentication company focused on the growing ... has been nominated for the 2015 New York Design ... The Design100, New York City Design Awards are ... are based on over 2,500 ratings from the marketplace, ...
(Date:4/13/2015)... 13, 2015  higi, a leading cloud-based consumer engagement ... fully engage with their communities around health and wellness, ... and secure API.  ... accessible, affordable, and convenient vehicle to receive validated health ... The API will allow higi,s trusted partners, ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3
... been found in male cichlid fish that evolved to lure ... the females mouths. A study in the online open access ... egg-like markings on the fins of cichlid fishes and uncovers ... the success of the fishes, exotic oral mating behaviour. ...
... TORONTO, ON Researchers are closer to understanding why ... they look, behave, think, and fight off disease, despite ... Innovative research from the University of Torontos ... new explanations for these glaring differences. In comparing brain ...
... The first State of the Carbon Cycle Report for North ... Science Program, finds the continents carbon budget increasingly overwhelmed by ... tons of carbon into the atmosphere each year, mostly as ... may remove up to half this amount, but these current ...
Cached Biology News:University of Toronto finds humans and chimps differ at level of gene splicing 2First-ever 'State of the Carbon Cycle Report' finds troubling imbalance 2
... is a high-quality four-place microplate shaker with ... speed is adjustable from 100 to 1350 ... a small orbit ensure effective shaking for ... quick and easy to set for 0 ...
... Ascent FL is equipped ... luminometric measurement technologies that ... of advanced features of ... Ascent. Fluoroskan Ascent FL ...
Rabbit polyclonal to STUB1 ( Abpromise for all tested applications). entrezGeneID: 10273 SwissProtID: Q9UNE7...
... stainless steel rack holders ... mechanism that permits selection ... angles, and "snap-in" product ... rack holder will accomodate ...
Biology Products: