Navigation Links
MIT reels in RNA surprise with microbial ocean catch
Date:5/24/2009

CAMBRIDGE, Mass.--An ingenious new method of obtaining marine microbe samples while preserving the microbes' natural gene expression has yielded an unexpected boon: the presence of many varieties of small RNAs snippets of RNA that act as switches to regulate gene expression in these single-celled creatures. Before now, small RNA could only be studied in lab-cultured microorganisms; the discovery of its presence in a natural setting may make it possible finally to learn on a broad scale how microbial communities living at different ocean depths and regions respond to environmental stimuli.

"Microbes are exquisite biosensors," said Edward Delong, a professor of civil and environmental engineering (CEE) and biological engineering. "We had developed this methodology to look at protein-encoding genes, because if we know which proteins the microbes are expressing under what conditions, we can learn about the environmental conditions and how these microbes influence those. The unexpected presence and abundance of these small RNAs, which can act as switches to regulate gene expression, will allow us to get an even deeper view of gene expression and microbial response to environmental changes.

DeLong and co-authors Yanmei Shi, a graduate student in CEE, and postdoctoral associate Gene Tyson describe this work in the May 14 issue of Nature. The team used a technique called metatranscriptomics, which allows them to analyze the RNA molecules of wild microbes, something that previously could be done only with lab-cultured microbes.

Microbes are ultra-sensitive environmental sensors that respond in the blink of an eye to minute changes in light, temperature, chemicals or pressure and modify their protein expression accordingly. But that sensitivity creates a quandary for the scientists who study them. Sort of like the observer effect in quantum physics, by entering the environment or removing the microbes from it, the observer causes the m
'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. SportCoatings; The North American Booster Club Association (NABCA); the Coatings Specialist Group New Booster Program Goes High Tech With Invisible Antimicrobial Defense
2. Innovative Fosshield(R) Antimicrobial Technology Shown to Continuously Kill MRSA Superbug
3. Baxter Receives 510(k) Clearance From FDA For V-Link With VitalShield, New Antimicrobial Intravascular Technology
4. Change in Medicare and Medicaid Legislation Creates Market for Antimicrobial Coatings In the U.S.
5. New Microbial Genome-to-Array Service
6. Advanced Analytical Unveils New Instrument for Rapid Microbial Identification at BIO 2008
7. Microtest Labs Doubles Microbial Identification, Analytical Services
8. 90 billion tons of microbial organisms live in the deep biosphere
9. Peramivir Phase 2 Data for the Treatment of Outpatient Influenza to be Presented at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy
10. Celsis Launches RapiScreen(TM) Beverage Microbial Screening System
11. PURE Bioscience and Ciba Strike New Contract for Natural Antimicrobial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... DIEGO , June 30, 2015  The ... Education in Biosciences (CCE/Bio) and UC San Diego ... fermentation, to be held Aug.  12 – 14, ... ).  This three-day workshop provides an intense exposure ... industrial biotechnology, and is well-suited to biologists, process ...
(Date:6/30/2015)...  The Dr. Samadi Prostate Cancer Center in ... suite of new genetic testing methods for men with an ... cancer. Dr. Samadi,s Prostate Cancer Center ... the risk and optimizing the diagnosis of prostate cancer, both ... now offer these revolutionary genetic tests to men with an ...
(Date:6/30/2015)... ... June 30, 2015 , ... ... media company, launched “Cannavoices,” an unprecedented digital video and broadcast initiative. Produced by ... the most dynamic collection of legal medical cannabis stories ever assembled. , ...
(Date:6/29/2015)... KY and Manhattan, KS (PRWEB) , ... June ... ... has acquired US PATENT 7736892 B2. Under the terms of the agreement, MediVet ... Umbilical Cord Matrix Stem Cells (UCMSCs). MB-007 is currently in pre-clinical development as ...
Breaking Biology Technology:UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 2New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 3New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 4New Revolutionary Genetic Testing for Prostate Cancer Offered at Dr. Samadi's Prostate Cancer Center 5Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 2Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 3MediVet Biologics Acquires Exclusive Patent License from Kansas State University 2MediVet Biologics Acquires Exclusive Patent License from Kansas State University 3
... of the fruit fly and roundworm,s functional genomic elements: DNA ... which genes are turned on and off at various times ... of the Human Genome Project, the genomes of the fruit ... elegans , are powerful models for understanding human biology ...
... (Nasdaq: NEOG ) announces the following Webcast:What: ... January 4, 2011 @ 11:00 ETWhere: , http://www.videonewswire.com/event.asp?id=75037 ... on to the web at the address above.  Contact: ... are unable to participate during the live webcast, the ...
... (December 21, 2010) -- A researcher known widely ... and use of minimally toxic, environmentally friendly chemicals ... Dr. Paul Anastas, science advisor to the ... for the EPA,s Office of Research and Development ...
Cached Biology Technology:Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes 2Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes 3Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes 4Science advisor to the US EPA to speak to industry, academic leaders on sustainability innovations 2Science advisor to the US EPA to speak to industry, academic leaders on sustainability innovations 3
(Date:6/24/2015)... MARTIGNY, Switzerland , June 24, 2015 /PRNewswire/ ... strategic partnership with emerging biometric password solution one ... http://photos.prnewswire.com/prnh/20150623/225014LOGO one face in, ... offers a ground-breaking and affordable multifactor-authentication biometric answer ... speaker recognition technology, provided in partnership with KeyLemon, ...
(Date:6/23/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/vq2k2f/bodyworn ... "Body-Worn Temperature Sensors Market - Global Industry Analysis, ... 2020" report to their offering. ... body-worn temperature sensors market. The global body-worn temperature ... of types, care setting, patient demographic, applications and ...
(Date:6/23/2015)... BEACH GARDENS, Fla. , June 23, ... multi-factor identity management and authentication solutions, today announced ... Altus strong, multi-factor authentication solution.  The enhancements ... of use of the DigitalPersona Altus platform ... biometric reader compatibility. In today,s ...
Breaking Biology News(10 mins):KeyLemon Announces Partnership With Biometric Password Solution onefacein 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2
... Hospital scientists has identified a possible new approach to ... component in a bid to invigorate the immune response. ... function of one of the innate immune molecules is ... response to infections and other threats. Investigators showed the ...
... Albert Einstein College of Medicine of Yeshiva University ... development of myelodysplastic syndromes (MDS), serious blood diseases that are ... leukemia. The findings could lead to targeted therapies against MDS ... the online edition of the journal Blood . ...
... The next "next-gen" technology in genome sequencing has gotten a ... Cold Spring Harbor Laboratory (CSHL) and collaborators today published results ... which was recently introduced but whose use has so far ... by CSHL Assistant Professor Michael Schatz and Adam Phillippy and ...
Cached Biology News:Innate immune system protein provides a new target in war against bacterial infections 2Innate immune system protein provides a new target in war against bacterial infections 3Myelodysplastic syndromes (MDS) linked to abnormal stem cells 2An error-eliminating fix overcomes big problem in '3rd-gen' genome sequencing 2An error-eliminating fix overcomes big problem in '3rd-gen' genome sequencing 3
Mouse monoclonal [3F8 ] to smooth muscle Myosin heavy chain I ( Abpromise for all tested applications). entrezGeneID: 4629 SwissProtID: P35749...
Rabbit polyclonal to pCrosstide (HRP) ( Abpromise for all tested applications)....
IkappaB-alpha (112B2) Mouse mAb...
Human sIL-2R/CD25 ELI-PAIR Kit...
Biology Products: