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MIGENIX releases CEO message #22
Date:2/15/2008

VANCOUVER and San Diego, CA, Feb. 15 /PRNewswire-FirstCall/ - MIGENIX Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage developer of drugs for infectious diseases, has issued its 22nd CEO Message from Jim DeMesa, MD, President & CEO. Today's CEO Message provides a discussion of the company's expected progress in 2008 and into 2009, including:

Omigard (prevention of catheter-related infections):

- Phase III results in H2/08

- NDA submission in H1/09

- Rest of world partnership

Celgosivir (hepatitis C virus):

- Phase II viral kinetics study results (including 600mg) in Q3/08

- Partnership

CLS001 (rosacea and other dermatologic conditions):

- Enter Phase III clinical development

MX-2401 (serious bacterial infections):

- Further advancement through preclinical development (clinicals

could begin in 2009)

To obtain a copy of the complete CEO Message, please visit the MIGENIX web site at http://www.migenix.com or contact Investor Relations at 1-800-665-1968, Extension 233 (also available on SEDAR and EDGAR).

About MIGENIX

MIGENIX is committed to advancing therapy, improving health, and enriching life by developing and commercializing drugs primarily in the area of infectious diseases. The Company's clinical programs include drug candidates for the treatment of chronic hepatitis C infections (Phase II and preclinical), the prevention of catheter-related infections (Phase III) and the treatment of dermatological diseases (Phase II). MIGENIX is headquartered in Vancouver, British Columbia, Canada with US operations in San Diego, California. Additional information can be found at http://www.migenix.com.

"Jim DeMesa"

James M. DeMesa, M.D.

President & CEO

FORWARD-LOOKING STATEMENTS

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