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MD Bioproducts Releases a New Mouse T1/ST2 ELISA
Date:3/29/2010

New ELISA offers a rapid method to quantitate T1/ST2 from mouse serum and cell culture supernate samples.

(PRWEB) March 24, 2010 -- MD Bioproducts, a division of MD Biosciences, Inc announces the launch of its new Mouse T1/ST2 ELISA for the study of inflammatory conditions. The ELISA offers researchers a rapid and accurate method to measure mouse serum and cell culture supernate levels of T1/ST2. The assay measures samples in the range of 0.156 – 10 ng/mL with a sensitivity of 0.05 ng/mL. Results can be obtained in less than 3 hours. In addition to the T1/ST2 ELISA, MD Bioproducts also offers researchers T1/ST2 antibodies for other related research applications such as IHC, western blotting, and flow cytometry.

ST2, also know as IL-1 R4 and T1 is an interleukin-1 receptor family glycoprotein that contributes to Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages and cardio myocytes. It binds IL-33, a cytokine that is up regulated by inflammation or mechanical strain in smooth muscle cells, keratinocytes, airway epithelia and cardiac fibroblasts. The soluble ST2 isoform is released by activated Th2 cells and strained cardiac myocytes and is elevated in the serum in allergic asthma. The roles of

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