Navigation Links
Lytix Biopharma and KAEL-GemVax Announce Joint Clinical Trial to Combine LTX-315 and GV1001 Cancer Immunotherapy
Date:6/19/2009

TROMS0, Norway and SEOUL, Korea, June 19 /PRNewswire/ -- The Norwegian biopharmaceutical company Lytix Biopharma and Korean company KAEL-GemVax today announced the signing of a collaborative agreement to test lead compounds LTX-315 and GV1001 as a combination therapy for the treatment of cancer.

According to Lytix Biopharma CEO Gunnar Saelid and KAEL-GemVax CEO Jay Sangjae Kim, "We are delighted to announce this joint venture to test a combination of two very interesting experimental drugs. In preclinical models, LTX-315 has demonstrated the ability to effect necrotic killing of cancer cells. Simulatenously it also causes the release of warning signals from the stressed and dying cells that trigger activation of the immune system. On the other hand GV1001, a telomerase peptide vaccine in phase III trials, is one of the best documented anti-cancer vaccines currently in development, with a potentially broad utility against a range of cancer types.

"There is a strong scientific rationale for combining these agents, providing a local inflammatory response combined with specific vaccination - these two novel agents should have the potential to function as an efficient immunotherapy for the treatment of cancer," says Mr Jon Amund Eriksen, Director of Product Development, Oncology at Lytix Biopharma. Mr Eriksen is also one of the key persons, together with Professor Gustav Gaudernack, at the Norwegian Radium Hospital involved in the development of GV1001.

Speaking on behalf of their respective companies, business development spokespeople Anders Fugelli (Lytix Biopharma) and Michelle Kyunghee Kim (KAEL-GemVax) comment, "KAEL-GemVax and Lytix Biopharma will both contribute scientific and regulatory, as well as financial, support to the planned study in patients, sharing the results for use in the future clinical development programs for each proprietary agent. Lytix Biopharma will be responsible for the design, set-up and conduct of the clinical study, which will run at the University Hospital of Northern Norway in Tromso. No further business commitments have been made at this stage."

The clinical phase I study will document the utility of LTX-315 as an immune stimulator in patients vaccinated with GV1001, a vaccine directed against the catalytic subunit of human telomerase. Telomerase is a universal tumour antigen expressed in 85-90% of cancer tissues.

    Corporate Enquiries:

    Anders Fugelli, PhD, Head of Business Development
    Tel +47-924-81-432

    Michelle Kyunghee Kim, Vice President, Business Development, KAEL-GemVax
    +82-2-540-6221



'/>"/>
SOURCE Lytix Biopharma AS
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Lytix Closes USD 10.4 Million Funding Round
2. ZyGEM and Advalytix Partner to Produce Innovative DNA Extraction Products
3. Wound Management Technologies, Inc. Announced Today That It Has Reached an Agreement in Principal to Acquire BioPharma Management Technologies, Inc.
4. Helix BioPharma Announces Q3 2009 Financial Results and Provides Product Development Update
5. PDL BioPharma Provides Second Quarter 2009 Revenue Guidance of Approximately $125 Million
6. Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients
7. Sinobiopharma Applies For Two Chinese Patents For Cisatracurium Besylate
8. Keryx Biopharmaceuticals Announces Appointment of Ron Bentsur as Chief Executive Officer
9. Sinobiopharma Updates on Progress; Projects Increases in Sales and Revenues In 2009
10. Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology
11. DOR BioPharma Reports 1st Quarter 2009 Financial Results and Reviews Recent Accomplishments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... 2016 NxGen MDx announced today that it brought its NxGen ... we,ve been able to improve customer service through shortened turnaround times and ... Mack , CEO of NxGen MDx. ... , A decrease in turnaround times ... more job opportunities at the Grand Rapid headquarters. The NxGen ...
(Date:12/5/2016)... Research and Markets has announced the ... Technologies, Markets and Companies" to their offering. ... , , ... human genome variations, development of sequencing technologies, and their applications. ... companies developing them. Various applications of sequencing are described including ...
(Date:12/4/2016)... ... 02, 2016 , ... A proposed five-year extension for programs ... research and development is welcome news for the photonics community, say leaders of ... part of the National Defense Authorization Act (NDAA) compromise agreement finalized today between ...
(Date:12/4/2016)... Dec. 3, 2016  In five studies being presented ... Annual Meeting and Exposition in San Diego ... to improve the delivery of life-saving treatments to patients ... are designed to carry therapies directly to the sites ... could provide a substantial advantage over traditional, systemic methods. ...
Breaking Biology Technology:
(Date:11/19/2016)... Securus Technologies, a leading provider of civil and criminal ... monitoring, announced today that it has offered a challenge ... technology judge determine who has the largest and best ... platform, and the best customer service. "ICSolutions ... we do – which clearly is not the case ...
(Date:11/15/2016)... 15, 2016 Research and Markets has announced ... 2021" report to their offering. ... ... by 2021 from USD 6.21 Billion in 2016, growing at a ... of the bioinformatics market is driven by the growing demand for ...
(Date:6/22/2016)... , June 22, 2016   Acuant ... and verification solutions, has partnered with RightCrowd ... solutions for Visitor Management, Self-Service Kiosks and ... products that add functional enhancements to existing ... corporations and venues with an automated ID ...
Breaking Biology News(10 mins):