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Lupus Research Institute Awards $3.6 Million for Novel Studies Driving Wide-Ranging New Science in Lupus
Date:2/15/2012

l to activate immune cells, and inhibiting the calcium increase causes profound immunosuppression.  We've discovered a potentially therapeutic role of calcium inhibition that could particularly benefit lupus patients. We're exploring whether treating mice with an inhibitor of a newly discovered subunit of calcium channel, a protein Orai1, induces regulatory T cells to prevent lupus autoimmunity while retaining protective immune responses to infection."
  • Dr. Janusz Kabarowski, University of Alabama, Birmingham: "We're investigating whether anti-inflammatory properties of HDL can be harnessed to protect the heart and blood vessels, and stem the immune system's attack on other organs. If so, therapies increasing HDL levels or improving its protective function could treat lupus nephritis."
  • About Lupus

    A complex autoimmune disease, lupus affects over 1.5-million Americans, primarily women.

    About the Lupus Research Institute

    The Lupus Research Institute (LRI), the world's leading private supporter of innovative research, pioneers discovery and champions scientific creativity to find solutions to lupus.


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