Navigation Links
Lupus Research Institute Awards $3.6 Million for Novel Studies Driving Wide-Ranging New Science in Lupus
Date:2/15/2012

/b>, Pennsylvania State University: "We recently found evidence for a link between inherited variations in sensitivity to male sex hormones (androgens) and some aspects of lupus in men. Our LRI study is exploring for the first time how differences in sensitivity to androgens might promote autoimmunity by allowing B cells to more easily switch to production of disease-causing autoantibodies. Since these same hormones are present in much lower amounts in women, we're also looking at whether such inherited differences in androgen sensitivity might influence the course of lupus in women."

Understanding Organ Damage

Three investigators will explore how the lupus immune system damages specific organs.  

  • Dr. Meggan Mackay, The Feinstein Institute of Medical Research: "This brain imaging study is the first testing whether autoantibodies against neurotransmitter receptor NMDA impair its activation. With Feinstein neuroimaging experts, we're using a new radiochemical tracer that binds the NMDA receptor to visualize receptor activity in the brains of lupus patients with this autoantibody. If successful, the technology will be developed as a new biomarker to diagnose neuropsychiatric lupus and monitor therapy response."
  • Dr. Mariana Kaplan, University of Michigan: "Our study lays the groundwork for therapies preventing cardiovascular disease in lupus. We're building on LRI-funded work showing high-density lipoprotein (HDL), 'good cholesterol,' is a risk factor for lupus-related cardiovascular disease. We're investigating in patients whether inflammation damages HDL, disrupting its protective effects on the heart and blood vessels."
  • Dr. Sandra Wolin, Yale University: "How does sunlight cause lupus skin flares? Many patients with lupus of the skin produce antibodies against a protein, Ro60, which normally binds RNA i
    '/>"/>

SOURCE Lupus Research Institute
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Trubion Pharmaceuticals, Inc. Announces Initiation of Phase 1 Study of SBI-087 for the Treatment of Systemic Lupus Erythematosus (SLE)
2. Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus
3. Human Genome Sciences to Host July 20 Conference Call to Discuss Top-Line Phase 3 Results for Benlysta(TM) (Formerly Lymphostat-B(R)) in Systemic Lupus Erythematosus
4. Biologic Agents Will Drive the Systemic Lupus Erythematosus Drug Market to More Than Quadruple to Nearly $2 Billion in 2018
5. Promise of a New Lupus Treatment Is a Groundbreaking Achievement
6. Lupus Research Institute: Benlysta(TM) Trial Results in an Historic Research Breakthrough and Victory for People With Lupus
7. deCODE Announces Agreement With Pfizer to Search for Variants in the Human Genome That Confer Risk of Systemic Lupus Erythematosis
8. Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018
9. Human Genome Sciences Europe Moves to the Cloud With Veeva CRM to Support New Lupus Treatment
10. Exagen Diagnostics Launches Cutting-Edge Lupus Diagnostic
11. NIH Funds $1M Research at Quest Product Development and University of Colorado for New Digitally-Controlled Endoscopes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... 27, 2015 In response to recent ... and The US Postal Service to no longer ... ,select agents, by the CDC, Marken reaffirmed today ... sensitive shipments. Marken uses its flexible ... and certified personnel to ensure the safe and ...
(Date:8/26/2015)... Aug. 26, 2015  Roka Bioscience, Inc. (NASDAQ: ... advanced testing solutions for the detection of foodborne pathogens, ... at the Sidoti & Company Emerging Growth Conference on ... held at the New York Marriott Marquis. ... available through the investor relations section of Roka Bioscience,s ...
(Date:8/26/2015)... Aug. 26, 2015 Intrexon Corporation (NYSE: ... the closing of its previously announced public offering of ... underwriters of their option to purchase an additional 731,707 ... of $41.00 per share.  The exercise of the underwriters, ... stock sold by Intrexon to 5,609,756 shares and increased ...
(Date:8/26/2015)... , August 26, 2015 ... biggest factors fueling the optimism in biotech,s forecast ... collaborations and life sciences advancements.  Active biotechnology & ... Pressure BioSciences, Inc. (OTCQB: PBIO), Sequenom, Inc. (NASDAQ: ... SRPT ), Raptor Pharmaceutical Corp. (NASDAQ: RPTP ...
Breaking Biology Technology:Marken Ensures Safe Transportation Of Select Agents And Toxins 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 3Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 4New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 2New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 3New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 4New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 5New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 6New Collaborations & Mergers For Research of Molecular Biomarkers in Human Diseases & Clinical Trials for Cancer Therapies Fueling Growth in Multi-Billion Dollar Life Sciences Market 7
... Thermo Fisher,Scientific Inc. (NYSE: TMO ), the world ... the 2008 Merrill Lynch Global Pharmaceutical,Biotechnology & Medical Device ... York City. The company will present on Thursday, February ... president and chief executive officer of Thermo,Fisher Scientific, will ...
... BD (Becton,Dickinson and Company) (NYSE: BDX ) announced ... today, elected Basil L. Anderson,Marshall O. Larsen, Gary A. ... of Directors. The BD Board currently consists of 13 ... Edward J. Ludwig,Chairman, President and Chief Executive Officer., ...
... SANTA CRUZ, Calif., Jan. 29 Expanding ... career resources to post-graduate and,alumni candidates, Bio Career ... joined forces., On Jan. 28, Emory University, ... Bio Career Center family, rounding out an,already elite ...
Cached Biology Technology:Thermo Fisher Scientific to Present at the 2008 Merrill Lynch Global Pharmaceutical, Biotechnology & Medical Device Conference 2BD Announces Results of Shareholder Votes at Annual Meeting 2Online Career Site for Life Science Professionals Continues Growth 2
(Date:8/4/2015)... 04, 2015 ... announced the addition of the "Digital ... Service), Sub-Segment (Computer Forensics, Network Forensics, Mobile ... Service, Vertical and Region - Global Forecast ... By Component (Hardware, Software, and ...
(Date:8/3/2015)... 2015 Synaptics, Inc. (Nasdaq: SYNA ), ... that members of the executive management team will present ... Technology Leadership Forum on Tuesday, August 11, 2015 at ... at the Sonnenalp Resort in Vail, CO. ... forward-looking information. An audio webcast of the event will ...
(Date:7/31/2015)... 2015 BGI llevará a cabo la 10ª Conferencia ... 25 de octubre de 2015, en Shenzhen, ... décimo aniversario este año. Desde su inauguración en 2006, ... anuales más influyentes del mundo en los campos de ... más dinámicas, entusiastas y amenas. ICG-10 se ...
Breaking Biology News(10 mins):Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3
... it survives on a diet of roundworm. But ... associate professor of biomedical engineering at the University of Tennessee, ... fighter. Zhang and his team have discovered that ... stimulating the immune system and killing tumors. The findings are ...
... NEW YORK, Dec. 4, 2012 A recent ABC News ... systems—to help ensure greater security in large childcare facilities. While ... stave off unwanted visitors and protect children from exiting the ... those who come in and out of the building. Slava ...
... of Seville (Spain) have developed a technique for estimating grape ... forward an index for identifying the ripeness of seeds without ... to decide the best moment for picking. The normal ... analysis. But this is a long and tedious task that ...
Cached Biology News:University of Tennessee researchers find fungus has cancer-fighting power 2Slava Volman Responds to Use of Biometrics for Security in Childcare Facilities 2A digital portrait for grapes indicates their ripeness 2
... (RNA polymers) are prepared ... of the enzyme, polynucleotide ... and the appropriate, ribonucleoside ... the exception of catalog ...
... Heavy duty stainless-steel shaker flask clips, ... high speeds. All clips are equipped ... (over 1L.) also include a bottom retainer ... prevent scratching of expensive glassware. Clips ...
RABBIT ANTI HUMAN ALPHA-2-ANTIPLASMIN...
... Bullseye Red Taq DNA Polymerase ... exhibits very high activity in primer extension ... contains a red dye which provides easy ... enzyme was added and allows confirmation of ...
Biology Products: