Navigation Links
Ludwig Institute for Cancer Research and Polaris Group Form Collaboration to Expand Development of Polaris' Novel Cancer Drug, ADI-PEG 20
Date:5/18/2011

NEW YORK and SAN DIEGO, May 18, 2011 /PRNewswire/ -- Ludwig Institute for Cancer Research LTD (LICR) and Polaris Group (Polaris) today announced the formation of a collaboration to expand development of Polaris' novel cancer drug, pegylated arginine deiminase (ADI-PEG 20). ADI-PEG 20 kills tumor cells by depletion of the amino acid arginine.

As part of the collaboration, LICR and Polaris will explore further the potential of ADI-PEG 20 as a cancer therapy and aim to identify other amino acid-degrading enzymes with anti-tumor activity.  The collaboration builds on an existing relationship under which LICR and Polaris have studied ADI-PEG 20 in melanoma and are currently conducting a Phase 2 clinical trial in small cell lung cancer (SCLC) that was initiated in December 2010.  LICR is the sponsor of the SCLC clinical trial, and LICR and Polaris are sharing expenses and resources to conduct this trial.

"We are delighted to have this agreement with Polaris," said Andrew Simpson, Ph.D., Scientific Director of LICR. "This collaboration builds on the work of Lloyd Old, M.D. of LICR and his seminal work on amino acid-degrading enzymes, including asparaginase and arginine deiminase, as anti-cancer treatments. We look forward to continuing our close working relationship with Polaris."

Bor-Wen Wu, Ph.D., Chief Executive Officer of Polaris, said, "This agreement is the fruit of many years of collaboration between LICR and Polaris, and is an opportunity to leverage the strengths of both organizations to attempt to bring ADI-PEG 20 to patients. In particular, I would like to thank Dr. Old for his vision, guidance and dedication to this project, and to his mentoring as we have moved ADI-PEG 20 from pre-clinical studies into human clinical trials."

Dr. Old commented: "The actions of antibodies and enzymes are remarkable for their high degree of specificity, and it is this property that makes them so attractive as potential anti-cancer agents
'/>"/>

SOURCE Polaris Group
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Polaris Group and The Ludwig Institute for Cancer Research Ltd Initiate Phase 2 Trial of Amino-Acid Degrading Enzyme, ADI-PEG 20, in Patients with Small Cell Lung Cancer
2. Northwest Biotherapeutics and the Fraunhofer Institute for Cell Therapy and Immunology are Partnering for Clinical Trials and Compassionate Use Cases in Europe
3. Larta Institute Receives Award for National Institutes of Health Commercialization Assistance Program at 2011 Acquisition, Grants, and Small Business Symposium
4. Van Andel Institute Earns Highest "Green Building" Award
5. LifeNet Health Breaks Ground on New Institute of Regenerative Medicine
6. The Wound Institute® to Feature Educational Forum on Dynamic Reciprocity During the Symposium on Advanced Wound Care and the Wound Healing Society Annual Meeting
7. MabVax Therapeutics Receives $1.8 Million in a Phase 2 Small Business Innovation Research Program Award From the National Cancer Institute
8. IBM and The Institute of Bioengineering and Nanotechnology Find Breakthrough for MRSA Treatment
9. Ontario Institute for Cancer Research Announces Investment in Microfluidics Technology for the Discovery of Anti-Cancer Drugs
10. Ontario Institute for Cancer Research Announces Enhancements to its Intellectual Property Development and Commercialization Program
11. Koch Institute for Integrative Cancer Research Dedicated Today
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... March 26, 2015 Ale Gicqueau, Founder ... Director of Clinical Affairs at Align Technology, on “ ... the upcoming ACRP 2015 Global Conference and Exhibition on ... Utah. , During the poster presentation, Ale Gicqueau ... and running a Postmarket Registry, the requirements and resources ...
(Date:3/25/2015)... Agnition announced today that it will be featured ... the first time at 7:30 a.m. CST March 31 ... the extremely important role soil microbes perform in crop ... Catalyst™ technology that enhances soil and plant health for ... again on April 28. , A biochemist at Agnition ...
(Date:3/25/2015)... 25, 2015 The surging prevalence ... have fuelled social media growth, with over 50% ... in social networking. Insurance companies are making use ... clients and promote a diversity of their services ... increasingly exploiting social networking services as part of ...
(Date:3/25/2015)... ROCKVILLE, Md. , March 25, 2015 ... been named a finalist for "Best Contract Research Organization" ... by the World Vaccine Congress. This ... as a finalist for the award, winning for "Best ... receiving a "Highly Recommended" distinction in 2013. ...
Breaking Biology Technology:Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2
... 5, 2011 Cord Blood America, Inc . ( ... umbilical cord blood stem cell preservation company focused ... families nationwide and internationally, is pleased to announce that the ... lawsuit filed by Cryo-Cell International against Cord Blood America, which ...
... 3, 2011 -- Researchers at the Hebrew University of Jerusalem ... successfully altering nanocrystal properties with impurity atoms -- a process ... of improved semiconductor nanocrystals. Semiconductor nanocrystals consist of ... than the width of a human hair. These tiny particles ...
... Calif., April 4, 2011 Ambry Genetics announced today ... (CSP) in Ion Torrent,s new service provider program. Ion ... are trusting with their samples has been trained and ... sequence data. (Logo: http://photos.prnewswire.com/prnh/20110307/LA59848LOGO ) ...
Cached Biology Technology:Cord Blood America: Court Grants Motion to Dismiss at Lawsuit Aimed at Blocking Acquisition 2'Nanocrystal doping' developed by Hebrew University researchers enhances semiconductor nanocrystals 2Ambry Genetics is First Authorized Customer Service Provider in New Ion Torrent CSP Program 2Ambry Genetics is First Authorized Customer Service Provider in New Ion Torrent CSP Program 3
(Date:3/12/2015)... , March 12, 2015 IriTech, a leading ... member of the Texas Instruments Design Network, announced today ... has demonstrated its IriShield USB MK2120U device during a ... for pension distribution. The iris scanner ... be marketed in India through ...
(Date:3/12/2015)... -- Beta Systems today announced Fast ... (IAM) solution for a fixed price and with ... IAM package, customers benefit from the 30 years, ... implementations across different industries. The new fixed-price IAM ... necessary services and consulting. It spans the implementation ...
(Date:3/11/2015)... 11, 2015 Research and Markets ( ... "Access Control Market by Product, Application & By Geography ... to their offering. , This report predicts ... $10.4 billion by 2020, with an estimated CAGR of ... the products types such as contact cards & readers, ...
Breaking Biology News(10 mins):Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2
... University of Adelaide study has identified the risk of ... reproductive technology. In the most comprehensive study of ... Robinson Institute have compared the risk of ... commonly available internationally, such as: IVF (in vitro fertilization), ...
... treatment and display heightened tumor-generating capacity can be identified by ... cells, a research team led by scientists at The University ... 3 edition of Cell Stem Cell . ... first time to separate low-PSA and high-PSA prostate cancer cells. ...
... a donated human retina to an Indiana University researcher ... helped uncover a previously undetected mechanism causing the disease. ... how millions of dollars are spent investigating the cause ... neovascularization. Working at IU,s Biocomplexity Institute, postdoctoral ...
Cached Biology News:Higher risk of birth defects from assisted reproduction 2Higher risk of birth defects from assisted reproduction 3Higher risk of birth defects from assisted reproduction 4Scientists identify prostate cancer stem cells among low-PSA cells 2Scientists identify prostate cancer stem cells among low-PSA cells 3Scientists identify prostate cancer stem cells among low-PSA cells 4Sloppy shipping of human retina leads IU researchers to discover new treatment path for eye disease 2Sloppy shipping of human retina leads IU researchers to discover new treatment path for eye disease 3Sloppy shipping of human retina leads IU researchers to discover new treatment path for eye disease 4
... The new MALDI O-TOF creates a new ... an orthogonal platform that has been licensed ... University of Manitoba. , As the first ... design and collisional cooling, the prOTOF 2000 ...
Rat Lung Fibroblasts (RLF) (>500,000 cells)...
Rat Aortic Endothelial Cells (RAOEC) (>500,000 cells)...
...
Biology Products: