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Lonza Withdraws Majority of Claims in Patent Lawsuit Against Northwest Biotherapeutics
Date:12/20/2007

used, Lonza's expression system. NWBT contracted to receive, and did receive, two batches of recombinant PSMA protein from the manufacturer. The PSMA protein that NWBT received was used in the manufacture of only one NWBT product: DCVax(R)-Prostate. The lots of DCVax(R)-Prostate product which involved these two batches of PSMA protein were used solely for early clinical trials in 1999 and 2000, and briefly in 2002, in the US. No other recombinant protein has ever been used to manufacture any other DCVax(R) product.

About Northwest Biotherapeutics

Northwest Biotherapeutics is a biotechnology company focused on developing immunotherapy products that treat cancers more effectively than current treatments, without toxicity, on a cost-effective basis. The Company has two broad platform technologies: dendritic cell-based vaccines, and therapeutic antibodies. The Company is currently conducting a large clinical trial in Glioblastoma multiforme, which is designed and powered to serve as a pivotal trial. The Company has also received clearance from the FDA for a large Phase III trial in prostate cancer, and clearance from the FDA for Phase I trials in five other cancers. The Company also has a second technology platform, involving monoclonal antibodies to CXCR4, which is at the late pre-clinical development stage.

For further information, please visit the company web site at http://www.nwbio.com.

Disclaimer

Statements made in this news release that are not historical facts are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as "expects," "believes," "intends," and similar expressions are intended to identify forward-looking statements. Such forward-looking statements include statements regarding the progress and NWBT's expectations concerning the pending litigation with Lonza Group AG. Actual results may differ materially from
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SOURCE Northwest Biotherapeutics, Inc.
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