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Living longer: Colon cancer patients gain time with radiofrequency ablation treatment
Date:3/16/2010

serious problem. Traditionally chemotherapy has been the only therapy. Radiofrequency ablation is a treatment that can destroy the tumor locally in the liver andin combination with systemic and local hepatic arterial chemotherapyit may extend the life of selected patients," he added.

"While the study did not make any direct comparisons to other treatments, survival rates after RFA were comparable to those of surgery," said Sofocleous. "We treated 56 patientsa highly selective population who had multiple prior treatments with surgery, systemic and local chemotherapyusing computed tomography- (CT) guided RFAover a six-year period and had survival rates of 91 percent at one year, 66 percent at two years and 41 percent at three years," said Sofocleous. More importantly, these survival ratesor life extensionsare in addition to the patients' survival rates after surgery," added the co-author of "Radiofrequency Ablation of Recurrent Colorectal Cancer Hepatic Metastases After Hepatectomy."

Radiofrequency ablation can be performed without affecting a patient's overall health, and most people can be discharged from the hospital within 24 hours and resume their usual activities in a few days. In this treatment, an interventional radiologist uses imaging to guide a needle through the skin into the tumor. The needle deposits radiofrequency energy into the target tissue, where it produces heat and kills the cancerous cells, sparing healthy tissue.

Medical records and relevant imaging were reviewed to determine technical success, complications and local tumor progression. Average tumor size was 1.9 centimeters, with average overall survival rate being 31 months. A modified clinical risk score was used to analyze the correlation with survival and local tumor progression according to nodal status of the primary cancer, interval from primary to liver metastases, number of tumors and size of the largest tumor ablated. Patients and tumor characteristics wi
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Contact: Maryann Verrillo
mverrillo@SIRweb.org
703-460-5572
Society of Interventional Radiology
Source:Eurekalert

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