Navigation Links
Limbs saved by menstrual blood stem cells
Date:8/18/2008

Cells obtained from menstrual blood, termed 'endometrial regenerative cells' (ERCs) are capable of restoring blood flow in an animal model of advanced peripheral artery disease. A study published today in BioMed Central's open access Journal of Translational Medicine demonstrates that when circulation-blocked mice were treated with ERC injections, circulation and functionality were restored.

Critical limb ischemia, an advanced form of peripheral artery disease, causes approximately 150,000 amputations per year in the US. Currently there are no medical or surgical interventions that are effective in the advanced stages of the disease. ERCs are cells taken from menstrual blood that are capable of forming into at least 9 different tissue types, including heart, liver and lung. Their discovery won the 'Medicine Research Award of the Year' award for BioMed Central's Research Awards in 2007.

Dr. Michael Murphy, a vascular surgeon from Indiana University and lead author of this study has already performed clinical trials with adult stem cells for patients with peripheral artery disease. He stated, "The advantage of ERCs is that they can be used in an 'off the shelf' manner, meaning they can be delivered to the point of care, do not require matching, and are easily injectable without the need for complex equipment."

The experiments were performed as a collaboration between University of Western Ontario, Scripps Research Institute, Indiana University, and several other academic centers. The ERC cell population is currently being developed by the US publicly traded company Medistem Inc, who supported these studies.

"We are proud of assembling such a strong, clinically experienced team to contribute to these studies" said Dr. Thomas Ichim, CEO of Medistem. "Dr. Ewa Carrier and Suman Kambhampati are hematologists who use stem cells on a regular basis, Dr. Angle is a vascular surgeon, who like Dr. Murphy sees CLI on a daily basis, and Dr. Amit Patel has performed numerous cardiac stem cell clinical trials. With such a team that understands not only the science, but also the practical implementation, we feel we are well positioned to translate this discovery into a practical therapy in the near future".


'/>"/>
Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-020-707-94804
BioMed Central
Source:Eurekalert

Related biology technology :

1. Physicists saved from drowning in complexities of wetting theory
2. Stem Cells From Menstrual Blood Show Therapeutic Potential
3. Biotest Diagnostics Receives FDA Clearance for Full Line of Traditional Blood Bank Reagents
4. FDA Grants Full Approval of PROCLEIX(R) ULTRIO(R) Blood Screening Assay
5. New CO-oximetry Module for the ABL80 FLEX Blood Gas Analyzer
6. Chest Physicians Now Suggest Early Intervention for Certain Blood Clots in DVT
7. GeneNews launches worlds first blood test for colorectal cancer screening
8. Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children
9. ProMetic announces Octapharma publication of PRDTS prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China
10. InterCure Supports AHA Endorsement of Home Blood Pressure Monitoring
11. Cord Blood America Reports CorCell, Its Major Acquisition in 2006, Turns Profitable
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/13/2017)... , ... January 13, 2017 , ... ... cuvette-related demand that it has found among its diverse customer base. The latest ... use in most brands electroporators including BTX and Bio-Rad. FireflySci is introducing three ...
(Date:1/12/2017)... North Carolina (PRWEB) , ... January 12, 2017 , ... ... called the Eureka Index – a process that evaluates the patent estate of a ... Immunolight LLC , a biomedical firm leading the way in technologies that transform ...
(Date:1/12/2017)... ... January 12, 2017 , ... ... 26-year-old Lisa Rosendahl’s doctors gave her only a few months to live. Now ... combination that has stabilized Rosendahl’s disease and increased both the quantity and quality ...
(Date:1/12/2017)... Pune, India , January 12, 2017 A new ... Type and End Users - Global Opportunity Analysis and Industry Forecast, 2014-2022," projects that ... $2,921 million in 2015, growing at a CAGR of 15.07% during the forecast period. ... ... Market Research Logo ...
Breaking Biology Technology:
(Date:1/11/2017)... 11, 2017 Intoxalock, a leading ignition interlock ... of its patent-pending calibration device. With this new technology, ... securely upload data logs and process repairs at service ... "Fighting drunk driving through the application of cutting-edge ... large, but also for the customer who can get ...
(Date:1/6/2017)... Jan. 5, 2017  Delta ID Inc., a leader ... technology for automotive at CES® 2017. Delta ID has ... to demonstrate the use of iris scanning as a ... the driver in a car, and as a way ... experience. Delta ID and Gentex will demonstrate ...
(Date:12/22/2016)... , Dec. 20, 2016  As part of its ... the leading personal genetics company, recently released its latest children,s ... . The book focuses on the topics of inheritance and ... Science Standards (NGSS) taught in elementary school classrooms in the ... a series by illustrator Ariana Killoran , whose previous ...
Breaking Biology News(10 mins):