Navigation Links
Life sticks: UC San Diego bioengineer's sticky insights published in journal Science
Date:4/9/2009

propriate mechanical context. The project began when he was approached by a surgeon puzzled by the results he was getting after injecting stem cells into damaged rat heart tissue in hopes of regenerating healthy heart tissue.

"As a matrix biologist and a mechanical engineer I said, 'Perhaps we need to look at what the host tissue is actually doing. What is being damaged and what is changing within the tissue due to the lack of oxygen?'" Engler and his collaborators found the cells in the damaged heart tissue were excreting collagen and making stiff scar tissue. "The engineer in me then analyzed the mechanical properties of the tissue and found out it was three to four times more rigid than the background healthy muscle. The biologist in me then characterized the cells in vitro and was able to show that these cells do respond to the mechanical properties of their environment."

Engler published his findings in 2006 in the high profile journal Cell and in the American Journal of Physiology. (Read New Scientist's description of Engler's findings.) One idea for improving such cell-based therapies, according to Engler, could involve injecting "smarter stem cells" that have been programmed to respond to some environmental stimuli but ignore other stimuli.


'/>"/>

Contact: Daniel Kane
dbkane@ucsd.edu
858-534-3262
University of California - San Diego
Source:Eurekalert  

Page: 1 2 3 4

Related biology technology :

1. NIH News Confirms Trend in Stem Cell Storage Facilities, says CEO of San Diego-based Bio-Matrix Scientific Group
2. Global Biopharmaceutical Leader in Peptide Research Expands Commitment in San Diego/U.S. With New R&D Facility and Ready-To-Market Prostate Cancer Treatment Degarelix
3. A Scientific Milestone: Sex of Dolphin at SeaWorld San Diego Determined Prior to Conception
4. Convey Computer™ Corporation Announces First Customer: University of California, San Diego at SC08 Conference
5. San Diego universities, government and industry rally around local Clean-Tech cluster
6. Genetic clock makers at UC San Diego publish their timepiece in Nature
7. Gable PR Honored by PRSA San Diego Chapter with Three Awards for Client Programs
8. DermTech and Rady Childrens Hospital-San Diego, Initiate Study to Understand Effects of Vitamin D as a Treatment for Atopic Dermatitis in Children and Young Adults
9. Althea Technologies Receives Fast Growth Honors: Deloitte Technology Fast 50 and San Diego Business Journal Fast 100 Awards for the Fifth Consecutive Year
10. Amicus Therapeutics Opens Research Facility in San Diego
11. San Diegos Original Biotech Company Celebrates 30th Anniversary With Reunion
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Life sticks: UC San Diego bioengineer's sticky insights published in journal Science
(Date:8/29/2014)... Due to a misstatement posted by the Family Resource ... Center, LLC ( ASCTC ) was reported as an entity ... benefit ALS patients. Because of ASCTC's exclusive focus on ... therapeutic applications, FRC listed ASCTC as one of several alternatives ... not to support research that requires the death of human ...
(Date:8/28/2014)... August 28, 2014 Best Sanitizers, Inc., ... the food processing industry, is asking industry professionals to ... comparison of the E2 soap they’re currently using to ... Soap . Hand hygiene is critical to fighting ... processing environment. Six key criteria are identified to evaluate ...
(Date:8/28/2014)... spintronics, an electronic which is not only based ... their spin and the spin-related magnetism. Spin-charge converters ... and vice versa. Recently, the research group of ... at Johannes Gutenberg University Mainz in collaboration with ... for the first time realised a new, efficient ...
(Date:8/28/2014)... , Aug. 28, 2014   SunTrust Robinson ... three industry veterans to its equity research team ... "Our ongoing expansion in equity research demonstrates our ... unique insights to enhance their investment decision making," ... at STRH.  "We continue to make significant investments ...
Breaking Biology Technology:The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 3Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2A new, tunable device for spintronics 2A new, tunable device for spintronics 3SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 3
... as humans and, just like us, bacteria have their own ... at the Society for General Microbiology,s spring meeting. Uncovering the ... keep industrial microbes at peak performance. Professor van der ... have spent the last three years working out the molecular ...
... conversion of sunlight to electricity could brighten the ... National Laboratory (Berkeley Lab) have found a new ... place in semiconductor thin-films. This new route to ... continues to plague conventional solid-state solar cells. ...
... ... bj-diagnostik, under its brand “DNA-Planet”, introduces a newly structured offer for ... the exact analysis necessary to solve the genetic kinship relation in ... based on the facts of each individual case. In addition, DNA-Planet ...
Cached Biology Technology:New path to solar energy via solid-state photovoltaics 2New path to solar energy via solid-state photovoltaics 3DNA-Planet Launches New Service for Customer-Individual Indirect DNA Paternity Testing and Kinship Analysis 2DNA-Planet Launches New Service for Customer-Individual Indirect DNA Paternity Testing and Kinship Analysis 3DNA-Planet Launches New Service for Customer-Individual Indirect DNA Paternity Testing and Kinship Analysis 4
(Date:8/28/2014)... 25 million kilometres of new roads will be built ... into Earth,s last wildernesses, where they bring an influx ... Now, an ambitious study has created a ,global roadmap, ... to balance the competing demands of development and environmental ... layer that estimates that natural importance of ecosystems and ...
(Date:8/28/2014)... the world to Global Warming, has called for atmospheric ... He says that Carbon Capture, combined with limits on ... global warming getting out of control over the next ... the call during his presentation to the International Carbon ... to discuss Carbon Capture and Storage. , He ...
(Date:8/28/2014)... Biologists at Ludwig-Maximilians-Universitaet (LMU) in Munich have assigned ... genus of predatory arthropods. These animals lived in ... than related forms found in Jurassic strata. ... their shallow marine habitat and were fossilized some ... other denizens of the Silurian seas although ...
Breaking Biology News(10 mins):Study shows where on the planet new roads should and should not go 2Study shows where on the planet new roads should and should not go 3Global warming pioneer calls for CO2 to be taken from atmosphere and stored underground 2Paleontology: Oldest representative of a weird arthropod group 2
... known as ovarian ,chocolate, cysts for the brown liquid ... recurrence is common, which can cause ongoing pain and ... a simple and effective remedy the oral contraceptive ... and Shelley Reilly from Auckland, New Zealand, highlight a ...
... that are helping fight a multi-front war on cancer may ... researchers said. Cancer and cardiovascular disease, both among top ... 90 inhibitors as a treatment could become additional common ground, ... "I think hsp90 inhibitors may be some of the ...
... the use of Chinese wolfberries to improve vision deficiencies that ... research assistant professor of human nutrition, is studying wolfberries and ... show that the fruit can lower the oxidative stress that ... "I would not say that wolfberries are a medicine, but ...
Cached Biology News:New cancer therapy may fight cardiovascular disease 2Study uses Chinese wolfberries to improve vision imperfections caused by type-2 diabetes 2Study uses Chinese wolfberries to improve vision imperfections caused by type-2 diabetes 3
...
Mouse monoclonal [CIG 3A11/5] to Cig2 (rating: *****) ( Abpromise for all tested applications)....
Rabbit polyclonal to CAMK 1D beta ( Abpromise for all tested applications). entrezGeneID: 57118 SwissProtID: Q5SQQ7...
Goat polyclonal to HNF4 ( Abpromise for all tested applications). Antigen: Synthetic peptide: RLSKTLVDMDMADY (Human) N terminal. Entrez GeneID: 3172 Swiss Protein ID: P41235...
Biology Products: