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Life Technologies Signs Exclusive License Agreement for TAL Effector Technology That Enables Synthetic Biologists to Precisely Control Gene Expression in Engineered Organisms
Date:6/10/2011

broad areas of research and development.

"A key factor in the successful design and functionality of synthetically-based organisms is the ability to precisely regulate their metabolic pathways," said Nathan Wood, Vice President of Synthetic Biology for Life Technologies.  "TAL Effector Technology can fulfill that need by offering the first molecular tool to reliably design control mechanisms in cells."

By unveiling the fundamental code that details how TAL Effectors target specific genomic regions, the technology's inventors have provided scientists with a powerful tool to specifically target and engineer precise genetic control and to predictably affect other cellular functions.

The ability to control expression in target areas within a genome is pivotal for synthetic biologists working to develop a variety of chemical-producing organisms for purposes that could help solve some of the world's preeminent challenges. Such applications may include the development of biofuels to decrease society's dependence on fossil fuels, new vaccines to improve human health, or higher-yielding food crops that are more resistant to changing weather patterns.

TAL Effector Technology, broadly licensed by Life Technologies, was developed in Germany and licensed originally by 2Blades for all applications in plants, and augments Life Technologies' growing portfolio of tools and capabilities it offers to the synthetic biology community. Life Technologies initially plans to make TAL Effector Technology available via its GeneArt gene synthesis portfolio. However, this enabling technology has far broader applications than synthetic biology and will be developed for use in many other fields such as bioproduction, stem cell research and drug discovery.

About Life Technologies (www.lifetec
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SOURCE Life Technologies Corporation
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