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Life Technologies Signs Exclusive License Agreement for TAL Effector Technology That Enables Synthetic Biologists to Precisely Control Gene Expression in Engineered Organisms
Date:6/10/2011

CARLSBAD, Calif., June 10, 2011 /PRNewswire/ -- Life Technologies Corporation has signed an exclusive license agreement for novel technology that enables synthetic biologists to effectively program and control the genetic circuitry in engineered pathways and organisms. This technology, discovered by the inventors while at Martin-Luther-Universitat Halle-Wittenberg in Germany, provides the ability to target and regulate expression within the genome and will enable researchers to more accurately study and engineer gene function to develop solutions for better healthcare, agriculture and energy.

The TAL Effector Technology license was jointly signed with inventors Jens Boch, Ulla Bonas, Thomas Lahaye and Sebastian Schornack, and the Two Blades Foundation (2Blades), which exclusively licensed plant research tool uses to Life Technologies and retains exclusive rights for commercial applications in plants. This license marks another step in the company's strategic initiative to expand its presence in the rapidly evolving synthetic biology market, which is estimated to reach up to $2.4 billion by 2013, according to a report by BCC Research.

Transcription Activator-Like (TAL) Effector Technology, first published in the Dec. 2009 issue of Science (Vol. 326), allows proteins to be designed to specifically target and bind to a desired sequence of DNA.  TAL code is similar to a navigation system for the genome, allowing pinpoint delivery of functional control elements to any specified sequence. The functional elements delivered to these areas can be used to regulate or engineer the genome to control cellular function, which will aid scientists in
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