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Life Technologies Showcases Leading Technologies for Cancer Research at the AACR Annual Meeting 2012
Date:4/1/2012

ll be presented by John Carpten, Ph.D., head of the Integrated Cancer Genomics Division at the Phoenix-based Translational Genomics Research Institute (TGen) on Monday, April 2 at 10:30 a.m. Life Technologies is supporting the study, which is revealing the diversity of genetic mutations in triple negative tumors.

Semiconductor sequencing of melanoma samples – George Watts, Ph.D., research assistant professor and co-director of the Genomics Shared Service at The University of Arizona Cancer Center, will present a poster demonstrating accurate, cost-effective sequencing of six commonly mutated genes in archived research samples from metastatic melanoma patients using the Life Technologies Ion Personal Genome Machine (PGM™) system.  The authors state that the study represents proof of principle for "next-generation sequencing to provide robust detection of mutations in fixed tumor samples." The poster will be presented April 2, Monday morning, from 8 a.m. to 12 p.m.

AmpliSeq panels accurately identify more than 700 mutations in patient samples – Marilyn Li, Ph.D., professor of molecular and human genetics and director of the Cancer Genetics Lab at Baylor College of Medicine, will present a poster demonstrating use of the Life Technologies Ion AmpliSeq™ cancer panels to sequence 12 archived tumor research samples including FFPE, bone marrow and cell line samples. The authors report that the panel accurately identified all known mutations previously detected using Pyrosequencing or Sanger sequencing and was sensitive enough to detect mutations at freque
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