Life Technologies developed the TaqMan® hPSC Scorecard™ Panel in collaboration with Dr. Meissner. He is the lead author of a study in the journal Cell (Vol. 144, No. 3, pp. 439-452, Feb. 4, 2011) who identified a range of expression levels among key genes associated with pluripotency. By measuring gene activity in ES and iPS cells against the study's gene expression range, Dr. Meissner's lab was able to accurately score cells for their potential to differentiate into particular cell lineages.
Standardizing characterization allows researchers to work more efficiently by enabling them to quickly identify the most promising cells. It also helps accelerate various applications, including development of "disease-in-a-dish" models from patient-derived cells, drug screening and eventual use of pluripotent cells as a renewable source for transplantation medicine.
"It has become increasingly critical for researchers to consistently and accurately characterize the cells they are working with, particularly to realize the promise of stem cell-based technology in drug discovery and clinical applications," said Chris Armstrong, Ph.D., General Manager and Vice President of Primary and Stem Cell Systems at Life Technologies. "As such, the launch of this novel characterization panel supports our continued commitment to provide our customers with the most innovative products across the pluripotent stem cell workflow."
Dr. Meissner will give a presentation on his lab's use of the TaqMan® hPSC Scorecard™ Panel during one of two Innovation Showcases Life Technologies will host at ISSCR in Room 257 A-B on June 14. His talk takes place from 12:30-1 p.m. The second Innovatio
|SOURCE Life Technologies Corporation|
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