Navigation Links
Life Technologies Launches Highly Efficient Stem Cell Reprogramming Technology
Date:6/15/2011

CARLSBAD, Calif., June 15, 2011 /PRNewswire/ -- Life Technologies Corporation today announced the launch of CytoTune™-iPS Reprogramming Kit -- research technology that provides far improved efficiency over standard methods to develop induced pluripotent stem cells (iPSCs) from human somatic cells. The ability to more easily create larger numbers of these embryonic stem cell-like cells can expedite basic research and studies that target specific diseases.

Widely accepted methods for turning adult skin cells, for example, into iPSCs involve benign virus vectors that are used to deliver reprogramming genes.  The process, however, is woefully inefficient (reprogramming efficiency rates for standard methods range between 0.00001-0.01 percent) and runs the risk of leading to unwanted mutations since the vectors must insert themselves into the host cell's DNA – essentially altering the genome and leaving "footprints."

The CytoTune™-iPS Reprogramming Kit is based on zero-footprint technology that employs an RNA virus developed by the Japanese firm DNAVEC Corporation.  The benign vectors effectively do their job without DNA integration and can generate iPSCs with about 1 percent efficiency.

"This technology is the most successful method my lab has used to generate iPSCs," said Keiichi Fukuda, Ph.D., M.D. Professor and Chief, Department of Cardiology, and Vice Dean at the Keio University School of Medicine, whose research team demonstrated the effectiveness of CytoTune's RNA vector in a study published in the journal Cell Stem Cell.  "Considering the high efficiency of iPSC generation and absence of integration of the vectors into the host genome, this method is definitely the most powerful tool av
'/>"/>

SOURCE Life Technologies Corporation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Palatin Technologies, Inc. Announces Presentation and Publication on Validation of Scale for Subjective Male Sexual Arousal
2. Merriman Capital Announces Sponsorship of Circadian Technologies on OTCQX
3. Fox Chase Cancer Center Signs Agreement with Life Technologies Corporation
4. Spherix to Present at the 5th Lippert/Heilshorn Life Sciences & Medical Technologies Virtual Conference on June 16
5. BioStorage Technologies Showcases First-Ever Mobile Biorepository - Relofleetâ„¢ at Drug Information Association Annual Meeting
6. Life Technologies Signs Exclusive License Agreement for TAL Effector Technology That Enables Synthetic Biologists to Precisely Control Gene Expression in Engineered Organisms
7. NIST contests in China put next-gen robot technologies to the test
8. Biochemist and Geneticist Ronald W. Davis Receives $500,000 Gruber Genetics Prize for Pioneering Work in the Development of Biotechnologies that Have Significantly Advanced the Fields of Molecular Genetics and Genomics
9. Reportlinker Adds Biochips and Microarrays - Technologies, markets and companies
10. BioStorage Technologies Expands U.S. Operations with Opening of New Biorepository Facility
11. Life Technologies Simplifies, Organizes and Speeds Analysis of Genomic Data Through Launch of New LifeScope Bioinformatics Software
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... 2014 Pipette.com announces their Holiday ... can submit their #HolidayInTheLab pictures for a chance to ... , For those struggling to think of a holiday ... in the Lab Contest provides the ideal holiday presents. ... to send pictures of their chemistree, holiday sweaters, as ...
(Date:12/24/2014)... , Dec. 23, 2014 Sigma-Aldrich Corporation ... the waiting period under the Hart-Scott-Rodino Antitrust Improvements ... expired on December 22, 2014, thereby completing the ... for the acquisition of the Company by Merck ... clearance satisfies another condition to closing the transaction, ...
(Date:12/22/2014)... Md. , Dec. 22, 2014 /PRNewswire/ ... SYN), a developer of pathogen-specific therapies for ... on protecting the microbiome, today announced positive ... Phase 1a clinical trial of SYN-004, the ... prevention of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... , Dec. 22, 2014  ( www.competitivehealth.com ) — ... online medical bill review and advocacy service, has signed ... FREE WellCard Savings discount health services marketplace. ... was more than they expected to pay. As part ... care costs, WellCard Savings is pleased to offer medical ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2
... Completes Restructuring and Two Divestitures of Non-Core Product ... Caliper Life,Sciences, Inc. (Nasdaq: CALP ) today ... completion of two product line divestitures: the,sale of ... $5.0,million and the sale of its Pharmaceutical Development ...
... -, MONTVALE, N.J. ,Nov. 10 Synvista,Therapeutics, Inc. ... M.D.,Ph.D., President and Chief Executive Officer of Synvista will ... November 11, at 2:25,p.m. Eastern Time. The event will ... Palace Hotel in New York City., Dr. Berkowitz ...
... RAPIDS, Mich., Nov. 10 The West Michigan ... the incorporation,and financing of a new medical device ... West Michigan Science & Technology offices in,Grand Valley ... will work to develop and commercialize novel surgical ...
Cached Biology Technology:Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 2Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 3Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 4Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 5Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 6Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 7Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 8Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 9Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 10Caliper Life Sciences Reports Third Quarter 2008 Results; Sharpens Growth Focus, Strengthens Balance Sheet and Reduces Costs 11Synvista Therapeutics to Present at the Rodman & Renshaw 10th Annual Healthcare Conference 2West Michigan's Newest Medical Device Company Receives Support from the West Michigan Science & Technology Initiative and EDF Ventures 2
(Date:12/11/2014)... PAUL, Minn. , Dec. 10, 2014 /PRNewswire/ ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ... Adding functional endpoints to toxicology studies ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and ... the addition of the "Biometrics Market in ... http://photos.prnewswire.com/prnh/20130307/600769 ... projects such as rural banking and upgradation of ... trends witnessed in the market. Besides the aforementioned ...
(Date:12/3/2014)... 2, 2014   Marvin Test Solutions , ... solutions for military, aerospace, and manufacturing organizations, today ... successful TS-900 PXI semiconductor test platform . ... high-end systems to customers at a fraction of ... traditional ATE. "Our semiconductor customers ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3
... used mouse mutants to define critical steps involved in learning ... two proteins and the specific steps they take to control ... other nerve cells. , The findings, published in the ... of evidence from the field. The study shows definitively that ...
... University have discovered that our ears use the most ... babbling brooks to wailing babies. These results represent a ... encoded for transmission to the brain, according to the ... and Views" editorial in the Feb. 23 issue of ...
... step towards understanding prostate disease, Melbourne scientists have grown ... study published in the March edition of Nature Methods ... human prostate tissue equivalent to that found in a ... of the study, Monash Institute of Medical Research (MIMR) ...
Cached Biology News:Picking apart how neurons learn 2Carnegie Mellon scientists show brain uses optimal code for sound 2Carnegie Mellon scientists show brain uses optimal code for sound 3Human prostate grown from embryonic stem cells 2
... 9001:2000 Certified USDA Research Registered OLAW Assured ... Training AALAS Certified Technicians Documentation ... Documentation Upon Request Focus CRP ... all your custom immunology service needs. ...
Request Info...
... IHC Protocol Development ,Antibody Titer and ... Animal or Human Cells and Tissues ... Tissues ,Peroxidase, Alkaline Phosphatase, Immunogold, and ... Microscopy ,Protein Localization in Transgenic Animals ...
Request Info...
Biology Products: