Navigation Links
Lexogen Showcases Analysis of the Transcriptome of Carriers of Pathological Variants That Cause Alzheimer's Disease
Date:5/30/2017

Alzheimer’s Disease (AD) is the result of complex interactions between risk factors that cause pleiotropic changes in molecular networks linking a host of biological processes. A variety of genetic factors have been shown to contribute to risk with varying degrees of penetrance. Variants in these genes confer a different transcriptomic profile, and mutation carriers clustered separately from their non-carrier siblings.

New evidences provide support for both neuronal and glial specific pathways contributing to pathogenesis. However, little is understood about how the genetic loci and molecular changes are organized into common networks. Understanding variant-specific effects is of an immense importance for the elucidation of the underlying biology of the Alzheimer Disease. Initial analysis reveals a transcriptional regulation module that link that early-onset autosomal dominant and late-onset sporadic genes.

In this webinar, participants will learn to identify confounding factors that can affect transcriptomic analyses and learn how to address them. They will also learn digital deconvolution approaches to infer cell composition from RNA-seq data and how transcriptomic profiles can reveal gene co-expression networks.

The speaker for this webinar will be Dr. Oscar Harari, an assistant professor in the Department of Psychiatry in Washington University in St Louis.

He received a doctorate in artificial intelligence from the University of Granada, and he was trained in genetics of neurodegeneration in the Lab of Alison Goate, Department of Psychiatry, Washington University in St Louis during his postdoc. In his current role he is the associate professor in the Department of Psychiatry in Washington University in St Louis, where his research is focused in the identification of omics factors implicated in complex neurodegenerative traits; in particular Alzheimer Disease.

LabRoots will host the event June 8, beginning at 10 a.m. PDT, 1:00 p.m. EDT, 7:00 p.m. CEST. To read more about this event, learn of the continuing education credits offered, or to register for free, click here.

About Lexogen:    
Lexogen is a transcriptomics and Next Generation Sequencing (NGS) company, focusing on the development of technologies for complete transcriptome sequencing. Its portfolio includes innovative molecular biology kits, software, and services for RNA-Seq.

Lexogen offers two types of sequencing library preparation kits. SENSE kits are for whole transcriptome sequencing and are suitable for anaylsis of mRNA and total RNA from intact RNA samples, as well as highly degraded and FFPE samples. QuantSeq library preparation kits are for 3’ mRNA-Seq and target-specific sequencing. All library preparation protocols are based on Lexogen’s proprietary technologies which eliminate the need for RNA or cDNA fragmentation, allowing to preserve superior strand-specificity (>99.9%) and enabling exceptionally rapid turnaround times.

Other products include SPLIT RNA Extraction Kit, TeloPrime Full-Length cDNA Amplification Kit, RiboCop rRNA Depletion Kit, Spike-in RNA Variant Control Mixes (SIRVs), and Mix2 RNA-Seq Data Analysis Software for highly accurate concentration estimates of gene isoforms. Lexogen is based in Vienna, Austria, and has a subsidiary in Greenland, NH, US.

ABOUT LABROOTS
LabRoots is the leading scientific social networking website, which provides daily scientific trending news and science-themed apparel, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Read the full story at http://www.prweb.com/releases/2017/05/prweb14367516.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related biology technology :

1. Lexogen Launches Quantitative RNA-Seq Service for Cost-efficient and Accurate Gene Expression Profiling
2. Miltenyi Biotec Showcases the Generation of Purified Human iPSC Derived Cardiomyocytes
3. Huffington’s Thrive Global Pop-Up Store Showcases uBiome Gut Explorer Kits for the Microbiome
4. Shimadzu Scientific Instruments Announces Product Showcases, Live Demos, Posters and Presentations at Pittcon 2016
5. Kobe Showcases Biomedical Innovation Cluster to Foreign Correspondents
6. Cole-Parmer Showcases Products to Meet Laboratory Challenges at ACHEMA
7. Revive Detox "Open House" Showcases Expert Team in Upscale Therapeutic Environment
8. SIRO Clinpharm Showcases Biometrics Capabilities at the SCDM 2014 Annual Conference in Las Vegas
9. Ikonopedia Showcases New MQSA Management System and Reporting Modules at Intensive Breast Ultrasound Meeting
10. Rice Lake Weighing Systems Showcases Metrology Solutions for the 2014 NCSL International Workshop & Symposium
11. New Genedata Expressionist for Mass Spectrometry Showcases at 2013 ASMS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2019)... ... September 17, 2019 , ... Geneticure, Inc., a Rochester Minnesota ... that the U.S. Patent and Trademark Office (USPTO) and European Patent Office (EPO) ... recommendations for hypertension treatment. , The patent applies to Geneticure’s first pharmacogenomics ...
(Date:9/11/2019)... (PRWEB) , ... September 09, 2019 , ... ... life sciences companies and government agencies, announced that its president and CEO Maryann ... of successful business leaders. , The Forbes Council accepted Gallivan based on the ...
(Date:9/8/2019)... ... September 04, 2019 , ... The Blavatnik ... today the three Winners and six Finalists of the 2019 Blavatnik Regional ... across New York, New Jersey, and Connecticut since 2007, the Blavatnik Regional Awards ...
(Date:8/29/2019)... ... August 28, 2019 , ... DuPont Nutrition ... solutions to attendees at the International Baking Industry Expo, September 8 to 11, ... optimizing production efficiency to cost and waste reduction and from maintaining freshness throughout ...
Breaking Biology Technology:
(Date:8/25/2019)... ... August 23, 2019 , ... Sierra Instruments is pleased ... to their online store are now live. Sierra has redesigned entry to the site ... format is more user-friendly and easier to navigate with streamlined menus and simple access ...
(Date:8/21/2019)... ... 2019 , ... AbSci, a revolutionary synthetic biology company with ... complex protein therapeutics, today announced the appointment of Fred Larimore, PhD, to Vice ... brings more than 30 years of experience in biopharmaceutical manufacturing and process development ...
(Date:8/19/2019)... , ... August 19, 2019 , ... ... tissues through the use of ultra-thin two dimensional slices which are placed on ... highly limited for complex tissues and complicated features such as vasculature and thus ...
Breaking Biology News(10 mins):