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Lexicon to Present at Two Major Healthcare Investor Conferences
Date:6/3/2010

THE WOODLANDS, Texas, June 3 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that Alan J. Main, Ph.D., Lexicon's executive vice president of pharmaceutical research, will present at two investor conferences next week in New York. Dr. Main will present at the 9th Annual Needham Healthcare Conference on Wednesday, June 9, 2010 10 a.m. Eastern Time; and at the Jefferies 2010 Global Life Sciences Conference on Friday, June 11, 2010 at 11 a.m. Eastern Time.  Investors can access a webcast of the Jefferies Conference presentation at www.lexpharma.com.

Needham & Company's Annual Healthcare Conference is a forum for institutional investors and venture capital firms to hear the latest updates from senior management teams of both public and private companies in the biotechnology, specialty pharmaceuticals, medical technology, and diagnostics sectors.  The Jefferies Global Life Sciences Conference will feature presentations from more than 350 public and private healthcare companies across the life sciences spectrum, including biotechnology, life science tools, medical devices, diagnostics, specialty pharmaceutical, and multi-national pharma.

About Lexicon

Lexicon is a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease.  Lexicon currently has four drug candidates in mid-stage development for diabetes, irritable bowel syndrome, carcinoid syndrome and rheumatoid arthritis, all of which were discovered by Lexicon's research team.  Lexicon has used its proprietary gene knockout technology to identify more than 100 promising drug targets.  Lexicon has focused drug discovery efforts on these biologically-validated targets to create its extensive pipeline of clinical and preclinical programs.  For additional information about Lexicon and its programs, please visit www.lexpharma.com.

Safe Harbor Statement

This press release contains "forward-looking" statements, including statements relating to Lexicon's growth and future operating results, discovery and development of products, strategic alliances and intellectual property, as well as other matters that are not historical facts or information.  All forward-looking statements are based on management's current assumptions and expectations and involve risks, uncertainties and other important factors, specifically including those relating to Lexicon's ability to successfully conduct preclinical and clinical development of its potential drug candidates, advance additional candidates into preclinical and clinical development, obtain necessary regulatory approvals, achieve its operational objectives, obtain patent protection for its discoveries and establish strategic alliances, as well as additional factors relating to manufacturing, intellectual property rights, and the therapeutic or commercial value of its drug candidates, that may cause Lexicon's actual results to be materially different from any future results expressed or implied by such forward-looking statements.  Information identifying such important factors is contained under "Factors Affecting Forward-Looking Statements" and "Risk Factors" in Lexicon's annual report on Form 10-K for the year ended December 31, 2009, as filed with the Securities and Exchange Commission.  Lexicon undertakes no obligation to update or revise any such forward-looking statements, whether as a result of new information, future events or otherwise.


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SOURCE Lexicon Pharmaceuticals, Inc.
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