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Lexicon Pharmaceuticals to Present at RBC Capital Markets Healthcare Conference
Date:12/10/2007

THE WOODLANDS, Texas, Dec. 10 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that a member of Lexicon senior management will participate in the RBC Capital Markets Healthcare Conference panel Going With Your Gut: New Treatments for GI Disorders at The Westin Times Square Hotel in New York, New York on Wednesday, December 12, 2007 at 8:00 a.m. Eastern Time.

A live audio webcast of the panel presentation may be accessed on Lexicon's corporate website at http://www.lexpharma.com. An archived version of the webcast will be available on the website through December 20, 2007.

About Lexicon

Lexicon is a biopharmaceutical company focused on the discovery and development of breakthrough treatments for human disease. Lexicon currently has clinical programs underway for such areas of major unmet medical need as irritable bowel syndrome, cognitive disorders, and rheumatoid arthritis. The company has used its proprietary gene knockout technology to discover more than 100 promising drug targets and create an extensive pipeline of clinical and preclinical programs in the therapeutic areas of diabetes and obesity, cardiovascular disease, psychiatric and neurological disorders, cancer, immune system disorders and ophthalmic disease. To advance the development and commercialization of its programs, Lexicon is working both independently and through collaborators including Bristol-Myers Squibb Company, Genentech, Inc. and N.V. Organon. For additional information about Lexicon and its programs, please visit http://www.lexpharma.com.

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