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Lexicon Announces Proposed Offering of 27,500,000 Shares of Common Stock
Date:10/7/2009

THE WOODLANDS, Texas, Oct. 7/PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that it is offering to sell, subject to market and other conditions, 27,500,000 shares of its common stock pursuant to an effective shelf registration statement, of which 16,412,613 shares are being offered through the underwriters and 11,087,387 shares are being offered to Invus, L.P., Lexicon's largest stockholder. Lexicon also intends to grant the underwriters a 30-day option to purchase up to an aggregate of 2,461,892 additional shares of common stock to cover over-allotments, if any. All of the shares in the offering are to be sold by Lexicon. Morgan Stanley will be acting as the sole book-runner for the offering, with Thomas Weisel Partners LLC acting as co-manager.

This press release does not constitute an offer to sell, or the solicitation of an offer to buy, these securities, nor will there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale is not permitted. The offering of these securities will be made only by means of a preliminary prospectus supplement and accompanying prospectus, copies of which may be obtained from Morgan Stanley & Co. Incorporated, Attn: Prospectus Department, 180 Varick Street, 2nd Floor, New York, New York 10014, telephone: (866) 718-1649, or by emailing prospectus@morganstanley.com.

The issuer has filed a registration statement (including a base prospectus) with the Securities and Exchange Commission, or SEC, for an offering to which this communication relates. Before you invest, you should read the prospectus in that registration statement and related prospectus supplements and other documents that the issuer has filed or will file with the SEC for more complet
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SOURCE Lexicon Pharmaceuticals, Inc.
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