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Latest breakthroughs in technology expand options for diagnosing and treating disease
Date:5/4/2010

pave the way for a specific NOTES indication for surgical devices. Other devices used, including a laparoscopic device, are FDA commercially-available devices.

Dr. Hungness will present these data on Tuesday, May 4 at 10 a.m. CT in 255-257, Ernest N. Morial Convention Center.

Efficacy of an Electrosurgical Endo-Knife with a Water-Jet Function for Colorectal Endoscopic Submucosal Dissection of Superficial Colorectal Neoplasms (Abstract 347i)

By comparing the results of large colorectal tumor removal via endoscopic submucosal dissection (ESD) with flexknife versus flushknife, researchers from Osaka Medical Center for Cancer and Cardiovascular Diseases in Japan have discovered that flushknife, an endoscopic device with a water jet function, is a superior tool for removing large colorectal tumors (>2cm) in one piece.

Removal of large colorectal tumors by conventional endoscopic resection (EMR) is difficult, so typically such tumors have been removed in fragments through this method or patients have undergone colorectomy. Endoscopic submucosal dissection (ESD) is a promising new endoscopic therapy that can remove large tumors in one piece. To ensure precise histological assessment and the removal of all tumor residue, removing tumors in one piece is preferable to removing them piecemeal.

While ESD is less invasive than colorectomy, it is a technically difficult procedure to perform, has a higher incidence of complications and requires a longer operation time than conventional EMR. Yoji Takeuchi, MD, of the department of gastrointestinal oncology at the Osaka Medical Center for Cancer and Cardiovascular Diseases sought to determine whether the flushknife could reduce the operation time without increasing adverse effects. He also wanted to determine whether the device could reduce the difficulty of the ESD procedure, thereby making it more accessible for patients.

Dr. Takeuchi and colleagues enrolled 49 patien
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Contact: Amy Levey
alevey@gymr.com
202-745-5116
Digestive Disease Week
Source:Eurekalert

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