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Latest Addition to Patent Portfolio Hammers Prescription Drug Abuse and Creates New Market
Date:5/17/2011

ormulation techniques to solve complex problems. Pisgah has identified salt forms of nearly all the commercial opiates used in prescription pain medications which will impart abuse deterrent features. The drug abuser will find it more difficult to separate the active ingredient from the dosage form, and the active ingredient will be far less soluble in the abuse-route mucosa (nasal, vaginal, rectal). However, it is important to note, the drug will perform properly when used as intended by oral administration -- and when taken as prescribed, the release of the drug is not accelerated by drinking alcohol.

As for an integrated commercial offering covering other popular pain medications, Pisgah is continuing their research efforts while aggressively pursuing a development program for hydrocodone / acetaminophen combination products. In laboratory testing, Pisgah has shown they can "adjust" the properties of the new salts to yield immediate or controlled release versions. In general, the drug development pathway can be quite tortuous with unexpected events occurring, such as the FDA's mandate to reduce acetaminophen levels in products like Pisgah is developing. Fortunately, Pisgah sees this change more as an opportunity than a difficulty. As Pisgah's President, Bill Bristol, commented, "The mandated lower levels of acetaminophen allows for our technology's benefits to shine and not to be eclipsed by the health issues raised by higher levels of acetaminophen in combination products."

With eighteen patent applications and more on the way, Pisgah's intellectual property stable continues to grow, and is applicable to dozens of abused prescription drugs. Pisgah's technology provides an integrated solution to three principal concerns within the medical community: 1) improving patient care; 2) reducing medical practice liability; and 3) reducing barriers for treating pain. Pisgah anticipates its new products will be well-received by all stakeholders interested i
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SOURCE Pisgah Laboratories, Inc.
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