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LX211 highlighted as potential disease modifying therapy for noninfectious uveitis
Date:10/29/2009

ate and manageable. Abnormal hair growth (hirsutism) was observed in 5% of patients. Otherwise the safety profile was similar to placebo, and triglycerides and cholesterol were not elevated.

"Non-infectious uveitis involving the posterior segment of the eye is a leading cause of vision loss and long-term disability and the fourth leading cause of legal blindness in the industrialized world" said Ulrich Grau, Ph.D., Lux Biosciences' President and Chief Executive Officer. "As the majority of patients are first diagnosed at ages under 40 years, the socio-economic burden of uveitis is higher than that of other serious ocular conditions such as AMD and diabetic macular edema. The results from these clinical trials suggest that LX211 may have the potential to significantly change the face of uveitis therapy, based on its ability to modify the course of the disease. This is analogous to the advent of disease-modifying anti-rheumatic drugs (DMARD's) and their impact on the course of rheumatoid arthritis."


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